| Title : Engineering a lipase B from Candida antactica with efficient perhydrolysis performance by eliminating its hydrolase activity - Wang_2017_Sci.Rep_7_44599 |
| Author(s) : Wang XP , Zhou PF , Li ZG , Yang B , Hollmann F , Wang YH |
| Ref : Sci Rep , 7 :44599 , 2017 |
|
Abstract :
A Ser105Ala mutant of the lipase B from Candida antarctica enables 'perhydrolase-only' reactions. At the example of the chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone, we demonstrate that with this mutant selective oxidation can be achieved in deep eutectic solvent while essentially eliminating the undesired hydrolysis reaction of the product. |
| PubMedSearch : Wang_2017_Sci.Rep_7_44599 |
| PubMedID: 28317884 |
Wang XP, Zhou PF, Li ZG, Yang B, Hollmann F, Wang YH (2017)
Engineering a lipase B from Candida antactica with efficient perhydrolysis performance by eliminating its hydrolase activity
Sci Rep
7 :44599
Wang XP, Zhou PF, Li ZG, Yang B, Hollmann F, Wang YH (2017)
Sci Rep
7 :44599