Title : The effects of topical ocular application of 0.25\% demecarium bromide on serum acetylcholinesterase levels in normal dogs - Ward_2003_Vet.Ophthalmol_6_23 |
Author(s) : Ward DA , Abney K , Oliver JW |
Ref : Vet Ophthalmol , 6 :23 , 2003 |
Abstract :
OBJECTIVE: To assess the effects of topical ocular application of 0.25% demecarium bromide on serum acetylcholinesterase (AChE) levels in normal dogs. ANIMALS: Nine adult mixed breed dogs weighing between 18 and 27 kg. PROCEDURES: Fifty micro L of 0.25% demecarium bromide were applied to one eye of each dog every 8 h for 6 days. Blood was analyzed for AChE levels prior to commencement of eye drops, and at 45 min, 1 h 45 min, 4 h 45 min, 1 day, 3 days, and 7 days following commencement of eye drops using a 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) reaction. |
PubMedSearch : Ward_2003_Vet.Ophthalmol_6_23 |
PubMedID: 12641839 |
Inhibitor | Demecarium |
Ward DA, Abney K, Oliver JW (2003)
The effects of topical ocular application of 0.25\% demecarium bromide on serum acetylcholinesterase levels in normal dogs
Vet Ophthalmol
6 :23
Ward DA, Abney K, Oliver JW (2003)
Vet Ophthalmol
6 :23