Title : Differential regulation of muscle acetylcholine receptor gamma- and epsilon-subunit mRNAs - Witzemann_1987_FEBS.Lett_223_104 |
Author(s) : Witzemann V , Barg B , Nishikawa Y , Sakmann B , Numa S |
Ref : FEBS Letters , 223 :104 , 1987 |
Abstract :
The contents of the mRNAs encoding the gamma- and epsilon-subunits of the nicotinic acetylcholine receptor as well as the single-channel properties of the receptor have been assessed in innervated, denervated and reinnervated rat muscle. The changes in abundance of the gamma- and epsilon-subunit mRNAs correlate with the changes in relative density of two classes of acetylcholine receptor channels. The results support the view that a switch in the relative abundance of the gamma- and epsilon-subunit mRNAs is a major mechanism in regulating the properties of acetylcholine receptor channels in muscle. |
PubMedSearch : Witzemann_1987_FEBS.Lett_223_104 |
PubMedID: 3666131 |
Witzemann V, Barg B, Nishikawa Y, Sakmann B, Numa S (1987)
Differential regulation of muscle acetylcholine receptor gamma- and epsilon-subunit mRNAs
FEBS Letters
223 :104
Witzemann V, Barg B, Nishikawa Y, Sakmann B, Numa S (1987)
FEBS Letters
223 :104