Full name : Numa Shosaku
First name : Shosaku
Mail : Department of Medical Chemistry, Kyoto University Faculty of Medicine
Zip Code :
City :
Country : Japan
Email :
Phone :
Fax :
Website : \/\/www.sciencedirect.com\/science\/article\/pii\/S0079612308623754
Directory :
Comment
Shosaku Numa was born in 1929 and passed away on february 15 1992. Numa pioneered the use of recombinant DNA technology to reveal the molecular structure of receptors and ion channels in excitable membranes. An obituary paper by Herbert Ladinsky retraces his achievements.
Title : Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel - Konno_1991_Proc.Biol.Sci_244_69 |
Author(s) : Konno T , Busch C , Von Kitzing E , Imoto K , Wang F , Nakai J , Mishina M , Numa S , Sakmann B |
Ref : Proc Biol Sci , 244 :69 , 1991 |
Abstract : |
PubMedSearch : Konno_1991_Proc.Biol.Sci_244_69 |
PubMedID: 1679551 |
Title : A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor - Imoto_1991_FEBS.Lett_289_193 |
Author(s) : Imoto K , Konno T , Nakai J , Wang F , Mishina M , Numa S |
Ref : FEBS Letters , 289 :193 , 1991 |
Abstract : |
PubMedSearch : Imoto_1991_FEBS.Lett_289_193 |
PubMedID: 1717313 |
Title : Selective coupling of different muscarinic acetylcholine receptors to neuronal calcium currents in DNA-transfected cells - Higashida_1990_Proc.Biol.Sci_242_68 |
Author(s) : Higashida H , Hashii M , Fukuda K , Caulfield MP , Numa S , Brown DA |
Ref : Proc Biol Sci , 242 :68 , 1990 |
Abstract : |
PubMedSearch : Higashida_1990_Proc.Biol.Sci_242_68 |
PubMedID: 1980742 |
Title : Spontaneous and agonist-induced openings of an acetylcholine receptor channel composed of bovine muscle alpha-, beta- and delta-subunits - Jackson_1990_Pflugers.Arch_417_129 |
Author(s) : Jackson MB , Imoto K , Mishina M , Konno T , Numa S , Sakmann B |
Ref : Pflugers Arch , 417 :129 , 1990 |
Abstract : |
PubMedSearch : Jackson_1990_Pflugers.Arch_417_129 |
PubMedID: 1707514 |
Title : Functional expression of the calcium release channel from skeletal muscle ryanodine receptor cDNA - Penner_1989_FEBS.Lett_259_217 |
Author(s) : Penner R , Neher E , Takeshima H , Nishimura S , Numa S |
Ref : FEBS Letters , 259 :217 , 1989 |
Abstract : |
PubMedSearch : Penner_1989_FEBS.Lett_259_217 |
PubMedID: 2557244 |
Title : Different sensitivities to agonist of muscarinic acetylcholine receptor subtypes - Bujo_1988_FEBS.Lett_240_95 |
Author(s) : Bujo H , Nakai J , Kubo T , Fukuda K , Akiba I , Maeda A , Mishina M , Numa S |
Ref : FEBS Letters , 240 :95 , 1988 |
Abstract : |
PubMedSearch : Bujo_1988_FEBS.Lett_240_95 |
PubMedID: 3142796 |
Title : Intracellular calcium release mediated by two muscarinic receptor subtypes - Neher_1988_FEBS.Lett_240_88 |
Author(s) : Neher E , Marty A , Fukuda K , Kubo T , Numa S |
Ref : FEBS Letters , 240 :88 , 1988 |
Abstract : |
PubMedSearch : Neher_1988_FEBS.Lett_240_88 |
PubMedID: 3192003 |
Title : Location of a region of the muscarinic acetylcholine receptor involved in selective effector coupling - Kubo_1988_FEBS.Lett_241_119 |
Author(s) : Kubo T , Bujo H , Akiba I , Nakai J , Mishina M , Numa S |
Ref : FEBS Letters , 241 :119 , 1988 |
Abstract : |
PubMedSearch : Kubo_1988_FEBS.Lett_241_119 |
PubMedID: 3197827 |
Title : Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance - Imoto_1988_Nature_335_645 |
Author(s) : Imoto K , Busch C , Sakmann B , Mishina M , Konno T , Nakai J , Bujo H , Mori Y , Fukuda K , Numa S |
Ref : Nature , 335 :645 , 1988 |
Abstract : |
PubMedSearch : Imoto_1988_Nature_335_645 |
PubMedID: 2459620 |
Title : Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes - Maeda_1988_FEBS.Lett_239_339 |
Author(s) : Maeda A , Kubo T , Mishina M , Numa S |
Ref : FEBS Letters , 239 :339 , 1988 |
Abstract : |
PubMedSearch : Maeda_1988_FEBS.Lett_239_339 |
PubMedID: 3181438 |
Title : Primary structure of porcine muscarinic acetylcholine receptor III and antagonist binding studies - Akiba_1988_FEBS.Lett_235_257 |
Author(s) : Akiba I , Kubo T , Maeda A , Bujo H , Nakai J , Mishina M , Numa S |
Ref : FEBS Letters , 235 :257 , 1988 |
Abstract : |
PubMedSearch : Akiba_1988_FEBS.Lett_235_257 |
PubMedID: 3402600 |
Title : Molecular basis of the functional heterogeneity of the muscarinic acetylcholine receptor - |
Author(s) : Numa S , Fukuda K , Kubo T , Maeda A , Akiba I , Bujo H , Nakai J , Mishina M , Higashida H |
Ref : Cold Spring Harbor Symposium on Quantitative Biology , 53 Pt 1 :295 , 1988 |
PubMedID: 3254775 |
Title : Effects of substitution of putative transmembrane segments on nicotinic acetylcholine receptor function - Tobimatsu_1987_FEBS.Lett_222_56 |
Author(s) : Tobimatsu T , Fujita Y , Fukuda K , Tanaka K , Mori Y , Konno T , Mishina M , Numa S |
Ref : FEBS Letters , 222 :56 , 1987 |
Abstract : |
PubMedSearch : Tobimatsu_1987_FEBS.Lett_222_56 |
PubMedID: 3653401 |
Title : Functional properties of nicotinic acetylcholine receptor subunits expressed in various combinations - Kurosaki_1987_FEBS.Lett_214_253 |
Author(s) : Kurosaki T , Fukuda K , Konno T , Mori Y , Tanaka K , Mishina M , Numa S |
Ref : FEBS Letters , 214 :253 , 1987 |
Abstract : |
PubMedSearch : Kurosaki_1987_FEBS.Lett_214_253 |
PubMedID: 2436944 |
Title : Differential regulation of muscle acetylcholine receptor gamma- and epsilon-subunit mRNAs - Witzemann_1987_FEBS.Lett_223_104 |
Author(s) : Witzemann V , Barg B , Nishikawa Y , Sakmann B , Numa S |
Ref : FEBS Letters , 223 :104 , 1987 |
Abstract : |
PubMedSearch : Witzemann_1987_FEBS.Lett_223_104 |
PubMedID: 3666131 |
Title : Molecular distinction between muscarinic acetylcholine receptor subtypes - Fukuda_1987_Nature_327_623 |
Author(s) : Fukuda K , Kubo T , Akiba I , Maeda A , Mishina M , Numa S |
Ref : Nature , 327 :623 , 1987 |
Abstract : |
PubMedSearch : Fukuda_1987_Nature_327_623 |
PubMedID: 3110621 |
Title : Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel - Imoto_1986_Nature_324_670 |
Author(s) : Imoto K , Methfessel C , Sakmann B , Mishina M , Mori Y , Konno T , Fukuda K , Kurasaki M , Bujo H , Fujita Y , Numa S |
Ref : Nature , 324 :670 , 1986 |
Abstract : |
PubMedSearch : Imoto_1986_Nature_324_670 |
PubMedID: 2432430 |
Title : Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels - Methfessel_1986_Pflugers.Arch_407_577 |
Author(s) : Methfessel C , Witzemann V , Takahashi T , Mishina M , Numa S , Sakmann B |
Ref : Pflugers Arch , 407 :577 , 1986 |
Abstract : |
PubMedSearch : Methfessel_1986_Pflugers.Arch_407_577 |
PubMedID: 2432468 |
Title : Molecular basis for the function of ionic channels - Numa_1986_Biochem.Soc.Symp_52_119 |
Author(s) : Numa S |
Ref : Biochemical Society Symposium , 52 :119 , 1986 |
Abstract : |
PubMedSearch : Numa_1986_Biochem.Soc.Symp_52_119 |
PubMedID: 2437927 |
Title : Molecular distinction between fetal and adult forms of muscle acetylcholine receptor - Mishina_1986_Nature_321_406 |
Author(s) : Mishina M , Takai T , Imoto K , Noda M , Takahashi T , Numa S , Methfessel C , Sakmann B |
Ref : Nature , 321 :406 , 1986 |
Abstract : |
PubMedSearch : Mishina_1986_Nature_321_406 |
PubMedID: 2423878 |
Title : Cloning and sequence analysis of human genomic DNA encoding gamma subunit precursor of muscle acetylcholine receptor - Shibahara_1985_Eur.J.Biochem_146_15 |
Author(s) : Shibahara S , Kubo T , Perski HJ , Takahashi H , Noda M , Numa S |
Ref : European Journal of Biochemistry , 146 :15 , 1985 |
Abstract : |
PubMedSearch : Shibahara_1985_Eur.J.Biochem_146_15 |
PubMedID: 3967651 |
Title : A physiological study on acetylcholine receptor expressed in Xenopus oocytes from cloned cDNAs - Takahashi_1985_J.Physiol.Paris_80_229 |
Author(s) : Takahashi T , Kuno M , Mishina M , Numa S |
Ref : Journal de Physiologie (Paris) , 80 :229 , 1985 |
Abstract : |
PubMedSearch : Takahashi_1985_J.Physiol.Paris_80_229 |
PubMedID: 3834076 |
Title : Role of acetylcholine receptor subunits in gating of the channel - Sakmann_1985_Nature_318_538 |
Author(s) : Sakmann B , Methfessel C , Mishina M , Takahashi T , Takai T , Kurasaki M , Fukuda K , Numa S |
Ref : Nature , 318 :538 , 1985 |
Abstract : |
PubMedSearch : Sakmann_1985_Nature_318_538 |
PubMedID: 2415826 |
Title : Primary structure of beta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence - Tanabe_1984_Eur.J.Biochem_144_11 |
Author(s) : Tanabe T , Noda M , Furutani Y , Takai T , Takahashi H , Tanaka K , Hirose T , Inayama S , Numa S |
Ref : European Journal of Biochemistry , 144 :11 , 1984 |
Abstract : |
PubMedSearch : Tanabe_1984_Eur.J.Biochem_144_11 |
PubMedID: 6548186 |
Title : Structural homology of Torpedo californica acetylcholine receptor subunits - Noda_1983_Nature_302_528 |
Author(s) : Noda M , Takahashi H , Tanabe T , Toyosato M , Kikyotani S , Furutani Y , Hirose T , Takashima H , Inayama S , Miyata T , Numa S |
Ref : Nature , 302 :528 , 1983 |
Abstract : |
PubMedSearch : Noda_1983_Nature_302_528 |
PubMedID: 6188060 |
Title : Primary structures of beta- and delta-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences - Noda_1983_Nature_301_251 |
Author(s) : Noda M , Takahashi H , Tanabe T , Toyosato M , Kikyotani S , Hirose T , Asai M , Takashima H , Inayama S , Miyata T , Numa S |
Ref : Nature , 301 :251 , 1983 |
Abstract : |
PubMedSearch : Noda_1983_Nature_301_251 |
PubMedID: 6687403 |
Title : Molecular structure of the nicotinic acetylcholine receptor - |
Author(s) : Numa S , Noda M , Takahashi H , Tanabe T , Toyosato M , Furutani Y , Kikyotani S |
Ref : Cold Spring Harbor Symposium on Quantitative Biology , 48 Pt 1 :57 , 1983 |
PubMedID: 6586363 |
Title : Primary structure of alpha-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence - Noda_1982_Nature_299_793 |
Author(s) : Noda M , Takahashi H , Tanabe T , Toyosato M , Furutani Y , Hirose T , Asai M , Inayama S , Miyata T , Numa S |
Ref : Nature , 299 :793 , 1982 |
Abstract : |
PubMedSearch : Noda_1982_Nature_299_793 |
PubMedID: 6182472 |