| Title : Biocatalysts for cascade reaction: porcine pancreas lipase (PPL)-catalyzed synthesis of bis(indolyl)alkanes - Xiang_2013_Amino.Acids_45_937 |
| Author(s) : Xiang Z , Liu Z , Chen X , Wu Q , Lin X |
| Ref : Amino Acids , 45 :937 , 2013 |
|
Abstract :
A cascade reaction between aldehydes and indole catalyzed by lipase from porcine pancreas Type II (PPL) in solvent mixture at 50 degrees C was reported for the first time. Some control experiments had been designed to demonstrate that the PPL was responsible for the cascade reaction. After the optimization of the stepwise process, a series of bis(indolyl)alkanes were prepared in moderate to excellent yields under the catalysis of PPL. |
| PubMedSearch : Xiang_2013_Amino.Acids_45_937 |
| PubMedID: 23860845 |
| Gene_locus related to this paper: pig-1plip |
| Gene_locus | pig-1plip |
Xiang Z, Liu Z, Chen X, Wu Q, Lin X (2013)
Biocatalysts for cascade reaction: porcine pancreas lipase (PPL)-catalyzed synthesis of bis(indolyl)alkanes
Amino Acids
45 :937
Xiang Z, Liu Z, Chen X, Wu Q, Lin X (2013)
Amino Acids
45 :937