Xiao_2009_Macromol.Biosci_9_713

Reference

Title : Systematic comparison of HEA and HEMA as initiators in enzymatic ring-opening polymerizations - Xiao_2009_Macromol.Biosci_9_713
Author(s) : Xiao Y , Takwa M , Hult K , Koning CE , Heise A , Martinelle M
Ref : Macromol Biosci , 9 :713 , 2009
Abstract :

Two initiators containing a cleavable ester bond were compared in the lipase-catalyzed ROP of CL and PDL. The results show that transesterification reactions are present at high rates throughout the enzymatic ROP and start at low conversion. HEA and HEMA displayed similar reaction efficiencies as initiators (acyl acceptors) in the enzymatic ROP. However, transacylation reactions on the HEA-initiated polyesters were found to be 15 times faster. While in both cases the amount of HEA- and HEMA-initiated polymers could be maximized by short reaction times, a well-defined (meth)acrylation by this approach was not possible. Our results show that transesterification reactions have to be considered when performing an enzyme-catalyzed ROP.

PubMedSearch : Xiao_2009_Macromol.Biosci_9_713
PubMedID: 19242919
Gene_locus related to this paper: canar-LipB

Related information

Substrate HEMA
Gene_locus HEMA    canar-LipB

Citations formats

Xiao Y, Takwa M, Hult K, Koning CE, Heise A, Martinelle M (2009)
Systematic comparison of HEA and HEMA as initiators in enzymatic ring-opening polymerizations
Macromol Biosci 9 :713

Xiao Y, Takwa M, Hult K, Koning CE, Heise A, Martinelle M (2009)
Macromol Biosci 9 :713