| Title : Half-inhibition concentrations of new cholinesterase inhibitors - Zdrazilova_2004_Z.Naturforsch.C_59_293 |
| Author(s) : Zdrazilova P , Stepankova S , Komers K , Ventura K , Cegan A |
| Ref : Z Naturforsch C , 59 :293 , 2004 |
|
Abstract :
The power of chosen carbamates and hydrazinium derivatives (carbazates) to inhibit the hydrolysis of acetylthiocholine by butyrylcholinesterase or acetylcholinesterase was tested. The determined pI50 values (= negative logarithm of the molar concentration inhibiting the enzyme activity by 50%) of the tested substances were compared with pI50 values of the commercially used drugs for the Alzheimer's disease treatment--rivastigmine and galanthamine. |
| PubMedSearch : Zdrazilova_2004_Z.Naturforsch.C_59_293 |
| PubMedID: 15241943 |
Zdrazilova P, Stepankova S, Komers K, Ventura K, Cegan A (2004)
Half-inhibition concentrations of new cholinesterase inhibitors
Z Naturforsch C
59 :293
Zdrazilova P, Stepankova S, Komers K, Ventura K, Cegan A (2004)
Z Naturforsch C
59 :293