| Title : A new and weakly antispasmodic protoberberine alkaloid from Rhizoma Coptidis - Zhao_2010_Phytother.Res_24_1414 |
| Author(s) : Zhao M , Xian YF , Ip SP , Fong HH , Che CT |
| Ref : Phytother Res , 24 :1414 , 2010 |
|
Abstract :
A new protoberberine alkaloid, 3-hydroxy-2-methoxy-9,10-methylenedioxy-8-oxo-protoberberine, along with three known compounds, was isolated from Rhizoma Coptidis. The new compound displayed weak antispasmodic activity against acetylcholine-induced contraction in isolated guinea-pig ileum with an IC50 of 83.7 microm. |
| PubMedSearch : Zhao_2010_Phytother.Res_24_1414 |
| PubMedID: 20564546 |
| Inhibitor | Berberine |
Zhao M, Xian YF, Ip SP, Fong HH, Che CT (2010)
A new and weakly antispasmodic protoberberine alkaloid from Rhizoma Coptidis
Phytother Res
24 :1414
Zhao M, Xian YF, Ip SP, Fong HH, Che CT (2010)
Phytother Res
24 :1414