| Title : Isoquinoline Alkaloids From Fibraurea recisa With Anti-acetylcholinesterase Activity - Zhao_2025_Chem.Biodivers__e03015 |
| Author(s) : Zhao K , Situ QY , Wang M , Zhu HH , Zhao HY , He JH , Tang Q , Zhang YB , Pei KH , Sun H , Wang GC |
| Ref : Chem Biodivers , :e03015 , 2025 |
|
Abstract :
Two new 8-oxoprotoberberine alkaloids (1 and 2), one new isoquinoline alkaloid (8), and a pair of enantiomeric isoindolebenzazepine alkaloids (10a and 10b) were isolated from the vine stems of Fibraurea recisa Pierre. Their structures and absolute configurations were elucidated by spectroscopic methods (mass spectrometry, ultraviolet, infrared, one- and two-dimensional nuclear magnetic resonance), quantum chemical electronic circular dichroism calculations, and single-crystal X-ray crystallography. All isolated compounds were evaluated for acetylcholinesterase inhibitory activity, with compound 4 exhibiting significant inhibition. |
| PubMedSearch : Zhao_2025_Chem.Biodivers__e03015 |
| PubMedID: 41264413 |
Zhao K, Situ QY, Wang M, Zhu HH, Zhao HY, He JH, Tang Q, Zhang YB, Pei KH, Sun H, Wang GC (2025)
Isoquinoline Alkaloids From Fibraurea recisa With Anti-acetylcholinesterase Activity
Chem Biodivers
:e03015
Zhao K, Situ QY, Wang M, Zhu HH, Zhao HY, He JH, Tang Q, Zhang YB, Pei KH, Sun H, Wang GC (2025)
Chem Biodivers
:e03015