| Title : A putative novel alpha\/beta hydrolase ORFan family in Bacillus - Siew_2005_FEBS.Lett_579_3175 |
| Author(s) : Siew N , Saini HK , Fischer D |
| Ref : FEBS Letters , 579 :3175 , 2005 |
|
Abstract :
A large number of sequences in each newly sequenced genome correspond to lineage and species-specific proteins, also known as ORFans. Amongst these ORFans, a large number are sequences with unknown structures and functions. We have identified a family of sequences, annotated as hypothetical proteins, which are specific to Bacillus and have carried out a computational study aimed at characterizing this family. Fold-recognition methods predict that these sequences belong to the alpha/beta hydrolase fold. We suggest possible catalytic triads for the ORFans and propose a hypothesis regarding the possible families within the alpha/beta hydrolase superfamily to which they may belong. |
| PubMedSearch : Siew_2005_FEBS.Lett_579_3175 |
| PubMedID: 15922334 |
| Family | Bacillus_lip |
Siew N, Saini HK, Fischer D (2005)
A putative novel alpha\/beta hydrolase ORFan family in Bacillus
FEBS Letters
579 :3175
Siew N, Saini HK, Fischer D (2005)
FEBS Letters
579 :3175