1. Home
  2. Reactivator
  3. 4-methyl-3-nitrobenzamido-pentyl-PAM-7d

4-methyl-3-nitrobenzamido-pentyl-PAM-7d

General

Type : Pyridine-aldoxime, Oxime

Chemical_Nomenclature : N-[5-[2-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]pentyl]-4-methyl-3-nitrobenzamide

Canonical SMILES : CC1=C(C=C(C=C1)C(=O)NCCCCC[N+]2=CC=CC=C2\/C=N\/O)[N+](=O)[O-]

InChI : InChI=1S\/C19H22N4O4\/c1-15-8-9-16(13-18(15)23(26)27)19(24)20-10-4-2-5-11-22-12-6-3-7-17(22)14-21-25\/h3,6-9,12-14H,2,4-5,10-11H2,1H3,(H,20,24)\/p+1

InChIKey : GLQZXKLUIAIZJA-UHFFFAOYSA-O

Other name(s) : 2-((hydroxyimino)methyl)-1-(5-(4-methyl-3-nitrobenzamido)pentyl)pyridin-1-ium iodide  ||  7d

MW : 371.17 || 371.41

Formula : C19H23N4O4

CAS_number :

PubChem : 163196903

UniChem : GLQZXKLUIAIZJA-UHFFFAOYSA-O

Target

Structure : 7QYN, 7R3C, 7R4E, 7R0A, 7R2F

Families : No family

References (1)

Title : Broad-spectrum antidote discovery by untangling the reactivation mechanism of nerve agent inhibited acetylcholinesterase - Lindgren_2022_Chemistry_28_e202200678
Author(s) : Lindgren C , Forsgren N , Hoster N , Akfur C , Artursson E , Edvinsson L , Svensson R , Worek F , Ekstrom , Linusson A
Ref : Chemistry , 28 :e202200678 , 2022
Abstract :
PubMedSearch : Lindgren_2022_Chemistry_28_e202200678
PubMedID: 35420233
Gene_locus related to this paper: mouse-ACHE