HGG-12
General
Type : Hagedorn Oxime, Oxime
Chemical_Nomenclature : [(E)-[1-[(3-benzoylpyridin-1-ium-1-yl)methoxymethyl]pyridin-2-ylidene]methyl]-oxoazanium\;diiodide
Canonical SMILES : C1=CC=C(C=C1)C(=O)C2=C[N+](=CC=C2)COCN3C=CC=CC3=C[NH+]=O.[I-].[I-]
InChI : InChI=1S\/C20H18N3O3.2HI\/c24-20(17-7-2-1-3-8-17)18-9-6-11-22(14-18)15-26-16-23-12-5-4-10-19(23)13-21-25\;\;\/h1-14H,15-16H2\;2*1H\/q+1\;\;\/p-1\/b19-13+\;\;
InChIKey : OYSGPEBWOFZIHL-BWSKXRJVSA-M
Other name(s) : Pyridinium, 1-(((3-benzoylpyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)-, diiodide || BDB-14 || MGG-12
MW : 603.19
Formula : C20H19I2N3O3
CAS_number : 83972-73-0
PubChem : 5492736
UniChem : OYSGPEBWOFZIHL-BWSKXRJVSA-M
Target
Structure : No structure
Families : No family
References (6)
| Title : [Comparative reactivation efficacy of the oximes HI-6 and HGG-12 in the central nervous system and blood of rats poisoned with nerve gases used in warfare] - |
| Author(s) : Pantelic D |
| Ref : Godisnjak Vojnomedicinske Akademije , 28 :35 , 1986 |
| PubMedID: 3482058 |
| Title : Bisquaternary pyridinium oximes as allosteric inhibitors of rat brain muscarinic receptors - Kloog_1985_Mol.Pharmacol_27_418 |
| Author(s) : Kloog Y , Sokolovsky M |
| Ref : Molecular Pharmacology , 27 :418 , 1985 |
| Abstract : |
| PubMedSearch : Kloog_1985_Mol.Pharmacol_27_418 |
| PubMedID: 3884998 |
| Title : PAM-2 Cl, HI-6, and HGG-12 in soman and tabun poisoning - Boskovic_1984_Fundam.Appl.Toxicol_4_S106 |
| Author(s) : Boskovic B , Kovacevic V , Jovanovic D |
| Ref : Fundamental & Applied Toxicology , 4 :S106 , 1984 |
| Abstract : |
| PubMedSearch : Boskovic_1984_Fundam.Appl.Toxicol_4_S106 |
| PubMedID: 6724203 |
| Title : Poster 77. On the in vitro interaction of sarin and soman with PAM-2, HI-6 and HGG-12 - |
| Author(s) : Rakin D , Tokovic B , Boskovic B |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984 |
| PubMedID: |
| Title : Poster 82. IR study of interaction of oximes HI-6, PAM-2 Cl and HGG-12 with soman, in vitro, in the presence and absence of cholinesterases - |
| Author(s) : Tokovic B , Cusic S , Radosevic P , Kojic J |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984 |
| PubMedID: |
| Title : Interactions of bisquaternary pyridine salts (H-oximes) with cholinergic receptors - Kuhnen-Clausen_1983_Arch.Toxicol_54_171 |
| Author(s) : Kuhnen-Clausen D , Hagedorn I , Gross G , Bayer H , Hucho F |
| Ref : Archives of Toxicology , 54 :171 , 1983 |
| Abstract : |
| PubMedSearch : Kuhnen-Clausen_1983_Arch.Toxicol_54_171 |
| PubMedID: 6661028 |