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Reactivator Report for: K869

in vitro K869 is a potent AChE and butyrylcholinesterase (BChE) reactivator


General
Type Oxime, Bispyridinium, Carboxamide
Chemical_Nomenclature 1-[4-[3-chloro-4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]butyl]pyridin-1-ium-4-carboxamide;dibromide
Canonical SMILES C1=C[N+](=CC=C1C(=O)N)CCCC[N+]2=CC(=C(C=C2)C=NO)Cl.[Br-].[Br-]
InChI InChI=1S/C16H17ClN4O2.2BrH/c17-15-12-21(10-5-14(15)11-19-23)7-2-1-6-20-8-3-13(4-9-20)16(18)22;;/h3-5,8-12H,1-2,6-7H2,(H-,18,22);2*1H
InChIKey HMGKZCJXJIYTOU-UHFFFAOYSA-N
Other name(s) CHEMBL4284764 ; BDBM50465904
________________________________________________________________________________________________
MW|494.6
Formula|C16H19Br2ClN4O2
CAS_number|
PubChem|145990366
UniChem|HMGKZCJXJIYTOU-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target

References:
Search PubMed for references concerning: K869
    Title: Determination of K869, a novel oxime reactivator of acetylcholinesterase, in rat body fluids and tissues by liquid-chromatography methods: Pharmacokinetic study
    Vanova N, Hojna A, Pejchal J, Herman D, Malinak D, Prchalova E, Musilek K, Karasova JZ
    Ref: J Pharm Sci, :, 2021 : PubMed

            


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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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