Bispyridinium

Pyridinium refers to the cation [C5H5NH]+. Often present in oximes as in the first reactivator of OP inhibited cholinesterase Pralidoxime (2-PAM). These are charged oximes which poorly cross the blood brain barrier. When two pyridinium molecules are joined by an appropriate linker one could bind to the PAS and the other attach the phosphorus of OP inhibited cholinesterase and eventually reactivate the enzyme
Reactivator name Formula Structure
K869

C16H19Br2ClN4O2

Triazole-annulated-oxime-3A

C19H22N7O2

Triazole-annulated-oxime-2A

C19H22N5O

Triazole-annulated-oxime-14A

C17H19N7O2

MB327

C21H3N2O

SAD-128

C20H30Cl2N2O

Ortho-7

C19H26N4O2-2+

K005

C15H18N4O2

K524

C28H34Br2N2

K792

C24H32Br2N2

K298

C26H30Br2N2

K344

C19H28Br2N2

K474

C25H40Br2N2

K131

C19H21Br2N3O || C19H21N3O

K142

C19H21Br2N3O

K153

C15H19Br2N3O

K454

C20H21Br2N3O

K456

C16H19Br2N3O2

K458

C15H19Br2N5O2

K727

C24H22Br2N4O2

K733

C22H24Br2N3O3

K117

C16H20N4O3+2

K127

C16H20Br2N4O3

K1833

K027-Cl2

C15H16Cl2N4O2+

K027

C15H18N4O2

K033

C16H20N4O2

K048

C16H20N4O2

K206

C16H17N4O2

K870

C16H16Cl2N4O2

K203

C16H18N4O2

K074

C14H16N4O2+2

K075

C16H18N4O2

K156

C14H17N3O

BDB-108

C16H18Br2N4O2

BI-6

C16H18N4O2

HI-6

C14H16Cl2N4O3 || C16H22N4O9S2

HLo-7

C15H17I2N5O4

HS-3

C14H16Cl2N4O3

HS-6

C14H16Cl2N4O3

DMB-4

C14H16N4O2+2

MMB-4

C13H14Br2N4O2

R665

C17H22I2N4O4

Trimedoxime

C15H18Br2N4O2

Toxogonin

C14H16Cl2N4O3