2OGZ

Name : Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor

Revelation date : 06-Mar-2007

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
"Sheehan, S.M., Mest, H.J., Watson, B.M., Klimkowski, V.J., Timm, D.E., Cauvin, A., Parsons, S.H."

Ligand :

References (1)

Title : Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site - Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765
Author(s) : Sheehan SM , Mest HJ , Watson BM , Klimkowski VJ , Timm DE , Cauvin A , Parsons SH , Shi Q , Canada EJ , Wiley MR , Ruehter G , Evers B , Petersen S , Blaszczak LC , Pulley SR , Margolis BJ , Wishart GN , Renson B , Hankotius D , Mohr M , Zechel JC , Michael Kalbfleisch J , Dingess-Hammond EA , Boelke A , Weichert AG
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :1765 , 2007
Abstract : Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765
ESTHER : Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765
PubMedSearch : Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765
PubMedID: 17239592
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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