2OPH
Name : Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor
Revelation date : 08-May-2007
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Duffy, J.L., Kirk, B.A,, Wang, L., Eiermann, G.J., He, H., Leiting, B., Lyons, K.A., Patel, R.A., Patel, S.B. et. al, and Weber, A.E.
Ligand : Inhibitor 4-aminocyclohexylalanine-derivative-25 Ligand in structure: Ligplot
References (1)
| Title : 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV - Duffy_2007_Bioorg.Med.Chem.Lett_17_2879 |
| Author(s) : Duffy JL , Kirk BA , Wang L , Eiermann GJ , He H , Leiting B , Lyons KA , Patel RA , Patel SB , Petrov A , Scapin G , Wu JK , Thornberry NA , Weber AE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :2879 , 2007 |
| Abstract : |
| PubMedSearch : Duffy_2007_Bioorg.Med.Chem.Lett_17_2879 |
| PubMedID: 17350841 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 2OPH Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 2OPH Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 2OPH Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 2OPH 3D, interactive encyclopedia of proteins - PROTEOPEDIA server