2QT9

Name : Human dipeptidyl peptidase IV\/CD26 in complex with 4-aryl cyclohexylanine inhibitor 2

Revelation date : 06-Nov-2007

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Kaelin, D.E., Smetin, A.L, Eiermann, G.J., He, H., Leiting, B., Lyons, K.A., Patel, R.A, Patel, S.B, Petrov, A., Scapin, G., Wu, J.K., Thornberry, N.A, Weber, A.E, Duffy, J.L.

Ligand :

References (1)

Title : 4-arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV - Kaelin_2007_Bioorg.Med.Chem.Lett_17_5806
Author(s) : Kaelin DE , Smenton AL , Eiermann GJ , He H , Leiting B , Lyons KA , Patel RA , Patel SB , Petrov A , Scapin G , Wu JK , Thornberry NA , Weber AE , Duffy JL
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :5806 , 2007
PubMedID: 17851076
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 2QT9 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 2QT9 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 2QT9 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 2QT9 3D, interactive encyclopedia of proteins - PROTEOPEDIA server