3C43

Name : Human dipeptidyl peptidase IV\/CD26 in complex with a flouroolefin inhibitor 1

Revelation date : 22-Apr-2008

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Scapin, G., Edmondson, S.D., Weber, A.E.

Ligand : Inhibitor Flouroolefin-1 Ligand in structure: Ligplot

References (1)

Title : Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors - Edmondson_2008_Bioorg.Med.Chem.Lett_18_2409
Author(s) : Edmondson SD , Wei L , Xu J , Shang J , Xu S , Pang J , Chaudhary A , Dean DC , He H , Leiting B , Lyons KA , Patel RA , Patel SB , Scapin G , Wu JK , Beconi MG , Thornberry NA , Weber AE
Ref : Bioorganic & Medicinal Chemistry Lett , 18 :2409 , 2008
Abstract :
PubMedSearch : Edmondson_2008_Bioorg.Med.Chem.Lett_18_2409
PubMedID: 18331795
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 3C43 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3C43 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3C43 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 3C43 3D, interactive encyclopedia of proteins - PROTEOPEDIA server