3DDU

Name : Prolyl Oligopeptidase with GSK552

Revelation date : 19-Aug-2008

Family : S9N_PPCE_Peptidase_S9

Gene_locus : human-PREP

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Madauss, Kevin P, Reid, Robert A, Haffner, Curt D, Miller, Aaron B

Ligand : Inhibitor DB07148 Ligand in structure: Ligplot

References (1)

Title : Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP) - Haffner_2008_Bioorg.Med.Chem.Lett_18_4360
Author(s) : Haffner CD , Diaz CJ , Miller AB , Reid RA , Madauss KP , Hassell A , Hanlon MH , Porter DJ , Becherer JD , Carter LH
Ref : Bioorganic & Medicinal Chemistry Lett , 18 :4360 , 2008
Abstract :
PubMedSearch : Haffner_2008_Bioorg.Med.Chem.Lett_18_4360
PubMedID: 18606544
Gene_locus related to this paper: human-PREPL

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 3DDU Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3DDU Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3DDU Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 3DDU 3D, interactive encyclopedia of proteins - PROTEOPEDIA server