3H0C
Name : Crystal Structure of Human Dipeptidyl Peptidase IV (CD26) in Complex with a Reversed Amide Inhibitor
Revelation date : 09-Jun-2009
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Nordhoff, Sonja, Cerezo-Galvez, Silvia, Deppe, Holger, Hill, Oliver, Lopez-Canet, Meritxell, Rummey, Christian, Thiemann, Meinolf, Matassa, Victor G., Edwards, Paul J., Feurer, Achim
Ligand : Inhibitor FPB-derived-7k Ligand in structure: Ligplot
References (1)
| Title : Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV - Nordhoff_2009_Bioorg.Med.Chem.Lett_19_4201 |
| Author(s) : Nordhoff S , Cerezo-Galvez S , Deppe H , Hill O , Lopez-Canet M , Rummey C , Thiemann M , Matassa VG , Edwards PJ , Feurer A |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4201 , 2009 |
| Abstract : |
| PubMedSearch : Nordhoff_2009_Bioorg.Med.Chem.Lett_19_4201 |
| PubMedID: 19515557 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 3H0C Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 3H0C Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 3H0C Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 3H0C 3D, interactive encyclopedia of proteins - PROTEOPEDIA server