3H0C

Name : Crystal Structure of Human Dipeptidyl Peptidase IV (CD26) in Complex with a Reversed Amide Inhibitor

Revelation date : 09-Jun-2009

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Nordhoff, Sonja, Cerezo-Galvez, Silvia, Deppe, Holger, Hill, Oliver, Lopez-Canet, Meritxell, Rummey, Christian, Thiemann, Meinolf, Matassa, Victor G., Edwards, Paul J., Feurer, Achim

Ligand :

References (1)

Title : Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV - Nordhoff_2009_Bioorg.Med.Chem.Lett_19_4201
Author(s) : Nordhoff S , Cerezo-Galvez S , Deppe H , Hill O , Lopez-Canet M , Rummey C , Thiemann M , Matassa VG , Edwards PJ , Feurer A
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4201 , 2009
PubMedID: 19515557
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 3H0C Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3H0C Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3H0C Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 3H0C 3D, interactive encyclopedia of proteins - PROTEOPEDIA server