Name : Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor

Revelation date : 06-Apr-2011

Family : Epoxide_hydrolase

Gene_locus : human-EPHX2

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Kurumbail, R.G., Williams, J.M.

Ligand : Inhibitor CHEMBL1689794 Ligand in structure: Ligplot

References (1)

Title : Discovery of potent inhibitors of soluble epoxide hydrolase by combinatorial library design and structure-based virtual screening - Xing_2011_J.Med.Chem_54_1211
Author(s) : Xing L , McDonald JJ , Kolodziej SA , Kurumbail RG , Williams JM , Warren CJ , O'Neal JM , Skepner JE , Roberds SL
Ref : Journal of Medicinal Chemistry , 54 :1211 , 2011
Abstract :
PubMedSearch : Xing_2011_J.Med.Chem_54_1211
PubMedID: 21302953
Gene_locus related to this paper: human-EPHX2

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 3PDC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3PDC Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3PDC Structural Classification Of Protein - SCOP server

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