Name : Crystal Structure of Dipeptidyl Peptidase IV (DPP4, DPP-IV, CD26) in Complex with Fab + sitagliptin
Revelation date : 12-Dec-2012
Family : DPP4N_Peptidase_S9
Gene_locus : ratno-dpp4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
An Inhibitory Antibody Against DPP IV Improves Glucose Tolerance in vivo - Validation of Large Molecule Approach for DPP IV Inhibition Tang, J., Majeti, J., Sudom, A., Xiong, Y., Lu, M., Liu, Q., Higbee, J., Zhang, Y., Wang, Y., Wang, W., Cao, P., Xia, Z., Johnstone, S., Yang, X., Yu, T., Sharkov, N., Walker, N., Tu, H., Shen, W., Wang, Z., Min, X. Merz, T., Gruetter. M. G.
Ligand : Inhibitor Sitagliptin Ligand in structure: Ligplot
Title : An Inhibitory Antibody against Dipeptidyl Peptidase IV Improves Glucose Tolerance in Vivo - Tang_2013_J.Biol.Chem_288_1307 |
Author(s) : Tang J , Majeti J , Sudom A , Xiong Y , Lu M , Liu Q , Higbee J , Zhang Y , Wang Y , Wang W , Cao P , Xia Z , Johnstone S , Min X , Yang X , Shao H , Yu T , Sharkov N , Walker N , Tu H , Shen W , Wang Z |
Ref : Journal of Biological Chemistry , 288 :1307 , 2013 |
Abstract : |
PubMedSearch : Tang_2013_J.Biol.Chem_288_1307 |
PubMedID: 23184939 |
Gene_locus related to this paper: ratno-dpp4 |
PDB-Sum : 4FFW Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 4FFW Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 4FFW Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 4FFW 3D, interactive encyclopedia of proteins - PROTEOPEDIA server