Name : Crystal Structure of Dipeptidyl Peptidase IV (DPP4, DPP-IV, CD26) in Complex with Fab + sitagliptin

Revelation date : 12-Dec-2012

Family : DPP4N_Peptidase_S9

Gene_locus : ratno-dpp4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

An Inhibitory Antibody Against DPP IV Improves Glucose Tolerance in vivo - Validation of Large Molecule Approach for DPP IV Inhibition Tang, J., Majeti, J., Sudom, A., Xiong, Y., Lu, M., Liu, Q., Higbee, J., Zhang, Y., Wang, Y., Wang, W., Cao, P., Xia, Z., Johnstone, S., Yang, X., Yu, T., Sharkov, N., Walker, N., Tu, H., Shen, W., Wang, Z., Min, X. Merz, T., Gruetter. M. G.

Ligand :

References (1)

Title : An Inhibitory Antibody against Dipeptidyl Peptidase IV Improves Glucose Tolerance in Vivo - Tang_2013_J.Biol.Chem_288_1307
Author(s) : Tang J , Majeti J , Sudom A , Xiong Y , Lu M , Liu Q , Higbee J , Zhang Y , Wang Y , Wang W , Cao P , Xia Z , Johnstone S , Min X , Yang X , Shao H , Yu T , Sharkov N , Walker N , Tu H , Shen W , Wang Z
Ref : Journal of Biological Chemistry , 288 :1307 , 2013
PubMedID: 23184939
Gene_locus related to this paper: ratno-dpp4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 4FFW Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 4FFW Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 4FFW Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 4FFW 3D, interactive encyclopedia of proteins - PROTEOPEDIA server