Rattus norvegicus (Rat) Dipeptidyl peptidase IV (DPP)
Belongs to peptidase family s9B || a very short sequence (fragment) from Cricetulus griseus (Chinese hamster) is almost identical Trembl Q99J96
Family : DPP4N_Peptidase_S9
Block : X
Position in NCBI Life Tree : Rattus norvegicus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Rattus N E > Rattus norvegicus N E > cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Rattus N E > Rattus norvegicus N E > cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Rattus N E > Rattus norvegicus N EMKTPWKVLLG LLGVAALVTI ITVPVVLLNK DEAAADSART YTLADYLKNT FRVKSYSLRW VSDSEYLYKQ ENNILLFNAE HGNSSIFLEN STFEIFGDSI SDYSVSPDRL FVLLEYNYVK QWRHSYTASY SIYDLNKRQL ITEEKIPNNT QWITWSQEGH KLAYVWKNDI YVKIEPHLPS HRITSTGKEN VIFNGINDWV YEEEIFGAYS ALWWSPNGTF LAYAQFNDTG VPLIEYSFYS DESLQYPKTV WIPYPKAGAV NPTVKFFIVN TDSLSSTTTT IPMQITAPAS VTTGDHYLCD VAWVSEDRIS LQWLRRIQNY SVMAICDYDK TTLVWNCPTT QEHIETSATG WCGRFRPAEP HFTSDGSSFY KIVSDKDGYK HICQFQKDRK PEQVCTFITK GAWEVISIEA LTSDYLYYIS NEYKEMPGGR NLYKIQLTDH TNKKCLSCDL NPERCQYYSV SLSKEAKYYQ LGCRGPGLPL YTLHRSTDQK ELRVLEDNSA LDKMLQDVQM PSKKLDFIVL NETRFWYQMI LPPHFDKSKK YPLLIDVYAG PCSQKADAAF RLNWATYLAS TENIIVASFD GRGSGYQGDK IMHAINKRLG TLEVEDQIEA ARQFLKMGFV DSKRVAIWGW SYGGYVTSMV LGSGSGVFKC GIAVAPVSRW EYYDSVYTER YMGLPTPEDN LDHYRNSTVM SRAENFKQVE YLLIHGTADD NVHFQQSAQI SKALVDAGVD FQAMWYTDED HGIASSTAHQ HIYSHMSHFL QQCFSLR
| Title : Structure-guided Discovery of Dual-recognition Chemibodies - Cheng_2018_Sci.Rep_8_7570 |
| Author(s) : Cheng AC , Doherty EM , Johnstone S , DiMauro EF , Dao J , Luthra A , Ye J , Tang J , Nixey T , Min X , Tagari P , Miranda LP , Wang Z |
| Ref : Sci Rep , 8 :7570 , 2018 |
| Abstract : |
| PubMedSearch : Cheng_2018_Sci.Rep_8_7570 |
| PubMedID: 29765112 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Structure-guided Discovery of Dual-recognition Chemibodies - Cheng_2018_Sci.Rep_8_7570 |
| Author(s) : Cheng AC , Doherty EM , Johnstone S , DiMauro EF , Dao J , Luthra A , Ye J , Tang J , Nixey T , Min X , Tagari P , Miranda LP , Wang Z |
| Ref : Sci Rep , 8 :7570 , 2018 |
| Abstract : |
| PubMedSearch : Cheng_2018_Sci.Rep_8_7570 |
| PubMedID: 29765112 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Structure-guided Discovery of Dual-recognition Chemibodies - Cheng_2018_Sci.Rep_8_7570 |
| Author(s) : Cheng AC , Doherty EM , Johnstone S , DiMauro EF , Dao J , Luthra A , Ye J , Tang J , Nixey T , Min X , Tagari P , Miranda LP , Wang Z |
| Ref : Sci Rep , 8 :7570 , 2018 |
| Abstract : |
| PubMedSearch : Cheng_2018_Sci.Rep_8_7570 |
| PubMedID: 29765112 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : An Inhibitory Antibody against Dipeptidyl Peptidase IV Improves Glucose Tolerance in Vivo - Tang_2013_J.Biol.Chem_288_1307 |
| Author(s) : Tang J , Majeti J , Sudom A , Xiong Y , Lu M , Liu Q , Higbee J , Zhang Y , Wang Y , Wang W , Cao P , Xia Z , Johnstone S , Min X , Yang X , Shao H , Yu T , Sharkov N , Walker N , Tu H , Shen W , Wang Z |
| Ref : Journal of Biological Chemistry , 288 :1307 , 2013 |
| Abstract : |
| PubMedSearch : Tang_2013_J.Biol.Chem_288_1307 |
| PubMedID: 23184939 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : An Inhibitory Antibody against Dipeptidyl Peptidase IV Improves Glucose Tolerance in Vivo - Tang_2013_J.Biol.Chem_288_1307 |
| Author(s) : Tang J , Majeti J , Sudom A , Xiong Y , Lu M , Liu Q , Higbee J , Zhang Y , Wang Y , Wang W , Cao P , Xia Z , Johnstone S , Min X , Yang X , Shao H , Yu T , Sharkov N , Walker N , Tu H , Shen W , Wang Z |
| Ref : Journal of Biological Chemistry , 288 :1307 , 2013 |
| Abstract : |
| PubMedSearch : Tang_2013_J.Biol.Chem_288_1307 |
| PubMedID: 23184939 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : An Inhibitory Antibody against Dipeptidyl Peptidase IV Improves Glucose Tolerance in Vivo - Tang_2013_J.Biol.Chem_288_1307 |
| Author(s) : Tang J , Majeti J , Sudom A , Xiong Y , Lu M , Liu Q , Higbee J , Zhang Y , Wang Y , Wang W , Cao P , Xia Z , Johnstone S , Min X , Yang X , Shao H , Yu T , Sharkov N , Walker N , Tu H , Shen W , Wang Z |
| Ref : Journal of Biological Chemistry , 288 :1307 , 2013 |
| Abstract : |
| PubMedSearch : Tang_2013_J.Biol.Chem_288_1307 |
| PubMedID: 23184939 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit - Backes_2007_Bioorg.Med.Chem.Lett_17_2005 |
| Author(s) : Backes BJ , Longenecker K , Hamilton GL , Stewart K , Lai C , Kopecka H , von Geldern TW , Madar DJ , Pei Z , Lubben TH , Zinker BA , Tian Z , Ballaron SJ , Stashko MA , Mika AK , Beno DW , Kempf-Grote AJ , Black-Schaefer C , Sham HL , Trevillyan JM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :2005 , 2007 |
| Abstract : |
| PubMedSearch : Backes_2007_Bioorg.Med.Chem.Lett_17_2005 |
| PubMedID: 17276063 |
| Gene_locus related to this paper: ratno-dpp4 , human-DPP4 |
| Title : Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit - Backes_2007_Bioorg.Med.Chem.Lett_17_2005 |
| Author(s) : Backes BJ , Longenecker K , Hamilton GL , Stewart K , Lai C , Kopecka H , von Geldern TW , Madar DJ , Pei Z , Lubben TH , Zinker BA , Tian Z , Ballaron SJ , Stashko MA , Mika AK , Beno DW , Kempf-Grote AJ , Black-Schaefer C , Sham HL , Trevillyan JM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :2005 , 2007 |
| Abstract : |
| PubMedSearch : Backes_2007_Bioorg.Med.Chem.Lett_17_2005 |
| PubMedID: 17276063 |
| Gene_locus related to this paper: ratno-dpp4 , human-DPP4 |
| Title : Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit - Backes_2007_Bioorg.Med.Chem.Lett_17_2005 |
| Author(s) : Backes BJ , Longenecker K , Hamilton GL , Stewart K , Lai C , Kopecka H , von Geldern TW , Madar DJ , Pei Z , Lubben TH , Zinker BA , Tian Z , Ballaron SJ , Stashko MA , Mika AK , Beno DW , Kempf-Grote AJ , Black-Schaefer C , Sham HL , Trevillyan JM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :2005 , 2007 |
| Abstract : |
| PubMedSearch : Backes_2007_Bioorg.Med.Chem.Lett_17_2005 |
| PubMedID: 17276063 |
| Gene_locus related to this paper: ratno-dpp4 , human-DPP4 |
| Title : Xanthine mimetics as potent dipeptidyl peptidase IV inhibitors - Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| Author(s) : Kurukulasuriya R , Rohde JJ , Szczepankiewicz BG , Basha F , Lai C , Jae HS , Winn M , Stewart KD , Longenecker KL , Lubben TW , Ballaron SJ , Sham HL , von Geldern TW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :6226 , 2006 |
| Abstract : |
| PubMedSearch : Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| PubMedID: 17010607 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors - Longenecker_2006_Biochemistry_45_7474 |
| Author(s) : Longenecker KL , Stewart KD , Madar DJ , Jakob CG , Fry EH , Wilk S , Lin CW , Ballaron SJ , Stashko MA , Lubben TH , Yong H , Pireh D , Pei Z , Basha F , Wiedeman PE , von Geldern TW , Trevillyan JM , Stoll VS |
| Ref : Biochemistry , 45 :7474 , 2006 |
| Abstract : |
| PubMedSearch : Longenecker_2006_Biochemistry_45_7474 |
| PubMedID: 16768443 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Xanthine mimetics as potent dipeptidyl peptidase IV inhibitors - Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| Author(s) : Kurukulasuriya R , Rohde JJ , Szczepankiewicz BG , Basha F , Lai C , Jae HS , Winn M , Stewart KD , Longenecker KL , Lubben TW , Ballaron SJ , Sham HL , von Geldern TW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :6226 , 2006 |
| Abstract : |
| PubMedSearch : Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| PubMedID: 17010607 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors - Longenecker_2006_Biochemistry_45_7474 |
| Author(s) : Longenecker KL , Stewart KD , Madar DJ , Jakob CG , Fry EH , Wilk S , Lin CW , Ballaron SJ , Stashko MA , Lubben TH , Yong H , Pireh D , Pei Z , Basha F , Wiedeman PE , von Geldern TW , Trevillyan JM , Stoll VS |
| Ref : Biochemistry , 45 :7474 , 2006 |
| Abstract : |
| PubMedSearch : Longenecker_2006_Biochemistry_45_7474 |
| PubMedID: 16768443 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Xanthine mimetics as potent dipeptidyl peptidase IV inhibitors - Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| Author(s) : Kurukulasuriya R , Rohde JJ , Szczepankiewicz BG , Basha F , Lai C , Jae HS , Winn M , Stewart KD , Longenecker KL , Lubben TW , Ballaron SJ , Sham HL , von Geldern TW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :6226 , 2006 |
| Abstract : |
| PubMedSearch : Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| PubMedID: 17010607 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors - Longenecker_2006_Biochemistry_45_7474 |
| Author(s) : Longenecker KL , Stewart KD , Madar DJ , Jakob CG , Fry EH , Wilk S , Lin CW , Ballaron SJ , Stashko MA , Lubben TH , Yong H , Pireh D , Pei Z , Basha F , Wiedeman PE , von Geldern TW , Trevillyan JM , Stoll VS |
| Ref : Biochemistry , 45 :7474 , 2006 |
| Abstract : |
| PubMedSearch : Longenecker_2006_Biochemistry_45_7474 |
| PubMedID: 16768443 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : The 3D structure of rat DPPIV\/CD26 as obtained by cryo-TEM and single particle analysis - Ludwig_2003_Biochem.Biophys.Res.Commun_304_73 |
| Author(s) : Ludwig K , Yan S , Fan H , Reutter W , Bottcher C |
| Ref : Biochemical & Biophysical Research Communications , 304 :73 , 2003 |
| Abstract : |
| PubMedSearch : Ludwig_2003_Biochem.Biophys.Res.Commun_304_73 |
| PubMedID: 12705886 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : The 3D structure of rat DPPIV\/CD26 as obtained by cryo-TEM and single particle analysis - Ludwig_2003_Biochem.Biophys.Res.Commun_304_73 |
| Author(s) : Ludwig K , Yan S , Fan H , Reutter W , Bottcher C |
| Ref : Biochemical & Biophysical Research Communications , 304 :73 , 2003 |
| Abstract : |
| PubMedSearch : Ludwig_2003_Biochem.Biophys.Res.Commun_304_73 |
| PubMedID: 12705886 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : The 3D structure of rat DPPIV\/CD26 as obtained by cryo-TEM and single particle analysis - Ludwig_2003_Biochem.Biophys.Res.Commun_304_73 |
| Author(s) : Ludwig K , Yan S , Fan H , Reutter W , Bottcher C |
| Ref : Biochemical & Biophysical Research Communications , 304 :73 , 2003 |
| Abstract : |
| PubMedSearch : Ludwig_2003_Biochem.Biophys.Res.Commun_304_73 |
| PubMedID: 12705886 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Molecular dissection of the NH2-terminal signal\/anchor sequence of rat dipeptidyl peptidase IV - Hong_1990_J.Cell.Biol_111_323 |
| Author(s) : Hong WJ , Doyle D |
| Ref : Journal of Cell Biology , 111 :323 , 1990 |
| Abstract : |
| PubMedSearch : Hong_1990_J.Cell.Biol_111_323 |
| PubMedID: 1974258 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Molecular dissection of the NH2-terminal signal\/anchor sequence of rat dipeptidyl peptidase IV - Hong_1990_J.Cell.Biol_111_323 |
| Author(s) : Hong WJ , Doyle D |
| Ref : Journal of Cell Biology , 111 :323 , 1990 |
| Abstract : |
| PubMedSearch : Hong_1990_J.Cell.Biol_111_323 |
| PubMedID: 1974258 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Molecular dissection of the NH2-terminal signal\/anchor sequence of rat dipeptidyl peptidase IV - Hong_1990_J.Cell.Biol_111_323 |
| Author(s) : Hong WJ , Doyle D |
| Ref : Journal of Cell Biology , 111 :323 , 1990 |
| Abstract : |
| PubMedSearch : Hong_1990_J.Cell.Biol_111_323 |
| PubMedID: 1974258 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Primary structure of rat liver dipeptidyl peptidase IV deduced from its cDNA and identification of the NH2-terminal signal sequence as the membrane-anchoring domain - Ogata_1989_J.Biol.Chem_264_3596 |
| Author(s) : Ogata S , Misumi Y , Ikehara Y |
| Ref : Journal of Biological Chemistry , 264 :3596 , 1989 |
| Abstract : |
| PubMedSearch : Ogata_1989_J.Biol.Chem_264_3596 |
| PubMedID: 2563382 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Primary structure of rat liver dipeptidyl peptidase IV deduced from its cDNA and identification of the NH2-terminal signal sequence as the membrane-anchoring domain - Ogata_1989_J.Biol.Chem_264_3596 |
| Author(s) : Ogata S , Misumi Y , Ikehara Y |
| Ref : Journal of Biological Chemistry , 264 :3596 , 1989 |
| Abstract : |
| PubMedSearch : Ogata_1989_J.Biol.Chem_264_3596 |
| PubMedID: 2563382 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : Primary structure of rat liver dipeptidyl peptidase IV deduced from its cDNA and identification of the NH2-terminal signal sequence as the membrane-anchoring domain - Ogata_1989_J.Biol.Chem_264_3596 |
| Author(s) : Ogata S , Misumi Y , Ikehara Y |
| Ref : Journal of Biological Chemistry , 264 :3596 , 1989 |
| Abstract : |
| PubMedSearch : Ogata_1989_J.Biol.Chem_264_3596 |
| PubMedID: 2563382 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : cDNA cloning for a bile canaliculus domain-specific membrane glycoprotein of rat hepatocytes - Hong_1987_Proc.Natl.Acad.Sci.U.S.A_84_7962 |
| Author(s) : Hong W , Doyle D |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :7962 , 1987 |
| Abstract : |
| PubMedSearch : Hong_1987_Proc.Natl.Acad.Sci.U.S.A_84_7962 |
| PubMedID: 3479775 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : cDNA cloning for a bile canaliculus domain-specific membrane glycoprotein of rat hepatocytes - Hong_1987_Proc.Natl.Acad.Sci.U.S.A_84_7962 |
| Author(s) : Hong W , Doyle D |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :7962 , 1987 |
| Abstract : |
| PubMedSearch : Hong_1987_Proc.Natl.Acad.Sci.U.S.A_84_7962 |
| PubMedID: 3479775 |
| Gene_locus related to this paper: ratno-dpp4 |
| Title : cDNA cloning for a bile canaliculus domain-specific membrane glycoprotein of rat hepatocytes - Hong_1987_Proc.Natl.Acad.Sci.U.S.A_84_7962 |
| Author(s) : Hong W , Doyle D |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :7962 , 1987 |
| Abstract : |
| PubMedSearch : Hong_1987_Proc.Natl.Acad.Sci.U.S.A_84_7962 |
| PubMedID: 3479775 |
| Gene_locus related to this paper: ratno-dpp4 |