4JNC
Name : Soluble Epoxide Hydrolase complexed with a carboxamide inhibitor
Revelation date : 05-Jun-2013
Family : Epoxide_hydrolase
Gene_locus : human-EPHX2
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Thalji, R.K., McAtee, J.J., Belyanskaya, S., Brandt, M., Brown, G.D., Costell, M.H., Ding, Y., Dodson, J.W., Eisennagel, S.H., Fries, R.E., Gross, J.W., Harpel, M.R., Holt, D.A., Israel, D.I., Jolivette, L.J., Krosky, D., Li, H., Lu, Q., Mandichak, T., Roethke, T., Schnackenberg, C.G., Schwartz, B., Shewchuk, L.M., Xie, W., Behm, D.J., Douglas, S.A., Shaw, A.L., Marino, J.P.
Ligand : Inhibitor CHEMBL2392714 Ligand in structure: Ligplot
References (1)
| Title : Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase - Thalji_2013_Bioorg.Med.Chem.Lett_23_3584 |
| Author(s) : Thalji RK , McAtee JJ , Belyanskaya S , Brandt M , Brown GD , Costell MH , Ding Y , Dodson JW , Eisennagel SH , Fries RE , Gross JW , Harpel MR , Holt DA , Israel DI , Jolivette LJ , Krosky D , Li H , Lu Q , Mandichak T , Roethke T , Schnackenberg CG , Schwartz B , Shewchuk LM , Xie W , Behm DJ , Douglas SA , Shaw AL , Marino JP, Jr. |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3584 , 2013 |
| Abstract : |
| PubMedSearch : Thalji_2013_Bioorg.Med.Chem.Lett_23_3584 |
| PubMedID: 23664879 |
| Gene_locus related to this paper: human-EPHX2 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 4JNC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 4JNC Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 4JNC Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 4JNC 3D, interactive encyclopedia of proteins - PROTEOPEDIA server