5YE8

Name : The crystal structure of human Lp-PLA2 in complex with a novel inhibitor

Revelation date : 25-Jul-2018

Family : PAF-Acetylhydrolase

Gene_locus : human-PLA2G7

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Liu, Q.F.,, Xu, Y.C.

Ligand :

References (1)

Title : Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2 - Liu_2017_J.Med.Chem_60_10231
Author(s) : Liu Q , Huang F , Yuan X , Wang K , Zou Y , Shen J , Xu Y
Ref : Journal of Medicinal Chemistry , 60 :10231 , 2017
Abstract : Liu_2017_J.Med.Chem_60_10231
ESTHER : Liu_2017_J.Med.Chem_60_10231
PubMedSearch : Liu_2017_J.Med.Chem_60_10231
PubMedID: 29193967
Gene_locus related to this paper: human-PLA2G7

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 5YE8 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 5YE8 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 5YE8 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 5YE8 3D, interactive encyclopedia of proteins - PROTEOPEDIA server