6B1E
Name : The structure of DPP4 in complex with Vildagliptin
Revelation date : 27-Sep-2017
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Berger, J.P., SinhaRoy, R., Pocai, A., Kelly, T.M., Scapin, G., Gao, Y.-D., Pryor, K.A.D., Wu, J., Eiermann, G.J., Xu, S., Zhang, X., Tatosian, D.A., Weber, A.E., Thornberry, N.A., Carr, R.D.
Ligand : Inhibitor Vildagliptin Ligand in structure: Ligplot
References (1)
| Title : A comparative study of the binding properties, dipeptidyl peptidase-4 (DPP-4) inhibitory activity and glucose-lowering efficacy of the DPP-4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice - Berger_2018_Endocrinol.Diabetes.Metab_1_e00002 |
| Author(s) : Berger JP , SinhaRoy R , Pocai A , Kelly TM , Scapin G , Gao YD , Pryor KAD , Wu JK , Eiermann GJ , Xu SS , Zhang X , Tatosian DA , Weber AE , Thornberry NA , Carr RD |
| Ref : Endocrinol Diabetes Metab , 1 :e00002 , 2018 |
| Abstract : |
| PubMedSearch : Berger_2018_Endocrinol.Diabetes.Metab_1_e00002 |
| PubMedID: 30815539 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 6B1E Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 6B1E Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 6B1E Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 6B1E 3D, interactive encyclopedia of proteins - PROTEOPEDIA server