6B1O

Name : The structure of DPP4 in complex with Vildagliptin Analog

Revelation date : 27-Sep-2017

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Berger, J.P., SinhaRoy, R., Pocai, A., Kelly, T.M., Scapin, G., Gao, Y.-D., Pryor, K.A.D., Wu, J., Eiermann, G.J., Xu, S., Zhang, X., Tatosian, D.A., Weber, A.E., Thornberry, N.A., Carr, R.D.

Ligand :

References (1)

Title : A comparative study of the binding properties, dipeptidyl peptidase-4 (DPP-4) inhibitory activity and glucose-lowering efficacy of the DPP-4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice - Berger_2018_Endocrinol.Diabetes.Metab_1_e00002
Author(s) : Berger JP , SinhaRoy R , Pocai A , Kelly TM , Scapin G , Gao YD , Pryor KAD , Wu JK , Eiermann GJ , Xu SS , Zhang X , Tatosian DA , Weber AE , Thornberry NA , Carr RD
Ref : Endocrinol Diabetes Metab , 1 :e00002 , 2018
PubMedID: 30815539
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 6B1O Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6B1O Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6B1O Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6B1O 3D, interactive encyclopedia of proteins - PROTEOPEDIA server