Name : Crystal structure of human Lecithin:cholesterol acyltransferase (LCAT) in complex with isopropyl dodec-11-enylfluorophosphonate (IDFP) and a small molecule activator supersedes 6DTJ

Revelation date : 05-Dec-2018

Family : PC-sterol_acyltransferase

Gene_locus : human-LCAT

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Manthei, K.A., Yang, S., Baljinnyam, B., Chang, L., Glukhova, A., Yuan, W., Freeman, L.A., Shen, M., Maloney, D.J., Schwendeman, A., Remaley, A.T., Jadhav, A., Tesmer, J.J.G. There is a preprint available at Biorxiv<\/A>

Ligand :

References (1)

Title : Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol - Manthei_2018_Elife_7_
Author(s) : Manthei KA , Yang SM , Baljinnyam B , Chang L , Glukhova A , Yuan W , Freeman LA , Maloney DJ , Schwendeman A , Remaley AT , Jadhav A , Tesmer JJ
Ref : Elife , 7 : , 2018
Abstract : Manthei_2018_Elife_7_
ESTHER : Manthei_2018_Elife_7_
PubMedSearch : Manthei_2018_Elife_7_
PubMedID: 30479275
Gene_locus related to this paper: human-LCAT

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server