6RT8

Name : Structure of catharanthine synthase - an alpha-beta hydrolase from Catharanthus roseus with a cleaviminium intermediate bound

Revelation date : 04-Mar-2020

Family : Plant_carboxylesterase

Gene_locus : catro-CS

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Caputi, L., Franke, J., Bussey, K., Farrow, S.C., Curcino Vieira, I.J., Stevenson, C.E.M., Lawson, D.M., O'Connor, S.E.

Ligand : Inhibitor 18-carboxymethoxy-cleaviminium Ligand in structure: Ligplot

References (1)

Title : Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids - Caputi_2020_Nat.Chem.Biol_16_383
Author(s) : Caputi L , Franke J , Bussey K , Farrow SC , Vieira IJC , Stevenson CEM , Lawson DM , O'Connor SE
Ref : Nat Chemical Biology , 16 :383 , 2020
Abstract :
PubMedSearch : Caputi_2020_Nat.Chem.Biol_16_383
PubMedID: 32066966
Gene_locus related to this paper: catro-CS , catro-TS , tabib-a0a5b8x6s2 , tabib-CorS

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 6RT8 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6RT8 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6RT8 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6RT8 3D, interactive encyclopedia of proteins - PROTEOPEDIA server