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Structure Report for: 2W6C

Name|AChE in complex with a bis-(-)-nor-meptazinol derivative
Revelation date|07-Apr-2009
Family|ACHE: there are 541 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Paz, A., Xie, Q., Greenblatt, H.M., Fu, W., Tang, Y., Silman, I., Qiu, Z., Sussman, J.L.
Ligand|Inhibitor: bis9-(-)-nor-meptazinol Ligand in structure: Ligplot


    Title: The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative reveals disruption of the catalytic triad
    Paz A, Xie Q, Greenblatt HM, Fu W, Tang Y, Silman I, Qiu Z, Sussman JL
    Ref: Journal of Medicinal Chemistry, 52:2543, 2009 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum2W6C Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2W6C Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2W6C Structural Classification Of Protein - SCOP server
PROTEOPEDIA2w6c 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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