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Structure Report for: 3PDC

Name|Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor
Revelation date|06-Apr-2011
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
Gene_locus|human-EPHX2
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Kurumbail, R.G., Williams, J.M.
Ligand|Inhibitor: CHEMBL1689794 Ligand in structure: Ligplot


Reference

    Title: Discovery of potent inhibitors of soluble epoxide hydrolase by combinatorial library design and structure-based virtual screening
    Xing L, McDonald JJ, Kolodziej SA, Kurumbail RG, Williams JM, Warren CJ, O'Neal JM, Skepner JE, Roberds SL
    Ref: Journal of Medicinal Chemistry, 54:1211, 2011 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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Databases

PDB-Sum3PDC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3PDC Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3PDC Structural Classification Of Protein - SCOP server
PROTEOPEDIA3pdc 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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