2,6-Dichlorophenolindophenyl-acetate

Chromogenic substrate for human AChE Km 38.0 microM and 244 pkat

General

Type : Acetate, Chromogen

Chemical_Nomenclature : [4-[(3,5-dichloro-4-oxocyclohexa-2,5-dien-1-ylidene)amino]phenyl] acetate

Canonical SMILES : CC(=O)OC1=CC=C(C=C1)N=C2C=C(C(=O)C(=C2)Cl)Cl

InChI : InChI=1S\/C14H9Cl2NO3\/c1-8(18)20-11-4-2-9(3-5-11)17-10-6-12(15)14(19)13(16)7-10\/h2-7H,1H3

InChIKey : TTWHMYKNQLOAIV-UHFFFAOYSA-N

Other name(s) : 2,6-Dichlorophenolindophenyl acetate  ||  2,6-dichloroindophenol acetate  ||  dichloroindophenol acetate  ||  DIPhA  ||  SCHEMBL18605938  ||  DTXSID80885276  ||  NSC90576  ||  ZINC4916805


MW : 310.1

Formula : C14H9Cl2NO3

CAS_number : 24857-20-3

PubChem : 259864

UniChem : TTWHMYKNQLOAIV-UHFFFAOYSA-N

Target

Structures : No structure

Families : ACHE, BCHE

References (6)

Title : A Smartphone Camera Colorimetric Assay of Acetylcholinesterase and Butyrylcholinesterase Activity - Pohanka_2021_Sensors.(Basel)_21_
Author(s) : Pohanka M , Zakova J
Ref : Sensors (Basel) , 21 : , 2021
Abstract :
PubMedSearch : Pohanka_2021_Sensors.(Basel)_21_
PubMedID: 33807562

Title : Evaluation of 2,6-dichlorophenolindophenol acetate as a substrate for acetylcholinesterase activity assay - Pohanka_2015_J.Enzyme.Inhib.Med.Chem_30_796
Author(s) : Pohanka M , Holas O
Ref : J Enzyme Inhib Med Chem , 30 :796 , 2015
Abstract :
PubMedSearch : Pohanka_2015_J.Enzyme.Inhib.Med.Chem_30_796
PubMedID: 25672529

Title : Spectrophotometric methods based on 2,6-dichloroindophenol acetate and indoxylacetate for butyrylcholinesterase activity assay in plasma - Pohanka_2013_Talanta_106_281
Author(s) : Pohanka M , Drtinova L
Ref : Talanta , 106 :281 , 2013
Abstract :
PubMedSearch : Pohanka_2013_Talanta_106_281
PubMedID: 23598128

Title : [How the various substrates activate the process of enzymatic hydrolysis by different cholinesterases] - Basova_2010_Zh.Evol.Biokhim.Fiziol_46_485
Author(s) : Basova NE , Rozengrart EV
Ref : Zh Evol Biokhim Fiziol , 46 :485 , 2010
Abstract :
PubMedSearch : Basova_2010_Zh.Evol.Biokhim.Fiziol_46_485
PubMedID: 21268878

Title : Indophenol Chromogenic Substrates of Cholinesterases of Different Origin - Rozengart_2002_J.Evol.Biochem.Physiol_38_16
Author(s) : Rozengart EV , Basova NE , Suvorov AA , Khovanskikh AE
Ref : Journal of Evolutionary Biochemistry and Physiology , 38 :16 , 2002
Abstract :
PubMedSearch : Rozengart_2002_J.Evol.Biochem.Physiol_38_16
PubMedID:

Title : [Different aspects of the substrate specificity of the cholinesterase in the optical ganglia of the Pacific Ocean squid Todarodes pacificus] - Rozengart_1996_Zh.Evol.Biokhim.Fiziol_32_384
Author(s) : Rozengart EV , Basova NE , Khovanskikh AE , Epshtein LM
Ref : Zhurnal Evoliutsionnoi Biokhimii i Fiziologii , 32 :384 , 1996
Abstract :
PubMedSearch : Rozengart_1996_Zh.Evol.Biokhim.Fiziol_32_384
PubMedID: 9054172