Astexin3-dC4
Lasso peptides are a large family of natural products formed by a side chain to backbone macrocyclization, resembling a knotted lasso. They have antibacterial activity. Astexin-3 treated with carboxypeptidase Y yields a truncated lasso peptide that lacked the C-terminal 4 amino acids E8RUP8_ASTEC ADU14098
General
Type : Peptide, Macrocycle
Chemical_Nomenclature : GPTPMVGLDSVSGQYWDQHA(PLAD)
Canonical SMILES :
InChI :
InChIKey :
Other name(s) :
MW :
Formula :
CAS_number :
PubChem :
UniChem :
Target
Structures : 5TXE
Families : ACPH_Peptidase_S9
References (1)
| Title : Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates - Chekan_2016_J.Am.Chem.Soc_138_16452 |
| Author(s) : Chekan JR , Koos JD , Zong C , Maksimov MO , Link AJ , Nair SK |
| Ref : Journal of the American Chemical Society , 138 :16452 , 2016 |
| Abstract : |
| PubMedSearch : Chekan_2016_J.Am.Chem.Soc_138_16452 |
| PubMedID: 27998080 |
| Gene_locus related to this paper: astec-e8rup5 |