Hcy-BChE
High specificity for BChE (with a 5.62-fold increase in fluorescence response compared to acetylcholinesterase). NIR emission intensity at 705 nm increases 46.6-fold. Detection limit: 8.31 10-2 U/mL
General
Type : Near-Infrared fluorescent Probe, Fluorescent Probe, Cyclobutyl, Xanthene, Indole
Chemical_Nomenclature : 2-[(1E)-2-[6-(cyclopropylcarbonyloxy)-2,3-dihydro-1H-xanthen-4-yl]ethenyl]-1-ethyl-3,3-dimethyl-3H-indol-1-ium
Canonical SMILES : C1=CC=C2C(=C1)C(C(=[N+]2CC)C=CC6=C3C(=CC4=C(O3)C=C(C=C4)OC(=O)C5CC5)CCC6)(C)C.[I-]
InChI : InChI=1S\/C31H32NO3.HI\/c1-4-32-26-11-6-5-10-25(26)31(2,3)28(32)17-15-20-8-7-9-23-18-22-14-16-24(19-27(22)35-29(20)23)34-30(33)21-12-13-21\;\/h5-6,10-11,14-19,21H,4,7-9,12-13H2,1-3H3\;1H\/q+1\;\/p-1
InChIKey : OLNZDEUMFALKQG-UHFFFAOYSA-M
Other name(s) : 2-[(E)-2-[6-(Cyclobutyroxy)-2,3-dihydro-1H-xanthen-4-yl]ethenyl]-1-ethyl-3,3-dimethyl-3H-indol-1-ium
Target
Structures : No structure
Families : BCHE
References (1)
| Title : Development of a novel near-infrared probe for butyrylcholinesterase accurate detection in vitro and in vivo - Bai_2026_Bioorg.Chem_178_109922 |
| Author(s) : Bai S , Feng B , Dong Q , Liu M |
| Ref : Bioorg Chem , 178 :109922 , 2026 |
| Abstract : |
| PubMedSearch : Bai_2026_Bioorg.Chem_178_109922 |
| PubMedID: 42096930 |