Isobutylene-oxide
Rat liver cytochrome P450 2E1 in the activation of 2-methylpropene (a gaseous alkene widely used in industry) to its epoxide 2-methyl-1,2-epoxypropane has been established. Epoxide hydrolase detoxify Isobutylene-oxide
General
Type : Epoxide
Chemical_Nomenclature : 2,2-dimethyloxirane
Canonical SMILES : CC1(CO1)C
InChI : InChI=1S\/C4H8O\/c1-4(2)3-5-4\/h3H2,1-2H3
InChIKey : GELKGHVAFRCJNA-UHFFFAOYSA-N
Other name(s) : 1,2-Epoxy-2-methylpropane || Isobutyleneoxide || Oxirane, 2,2-dimethyl- || 2-Methyl-1,2-epoxypropane || dimethyloxirane || Isobutylene oxide || Isobutylene epoxide || CHEBI:193943
MW : 72.11
Formula : C4H8O
CAS_number : 558-30-5
PubChem : 11208
UniChem : GELKGHVAFRCJNA-UHFFFAOYSA-N
Target
Structures : No structure
Families : Epoxide_hydrolase
References (1)
| Title : Species-dependent differences in biotransformation pathways of 2-methylpropene (isobutene) - Cornet_1995_Chem.Res.Toxicol_8_987 |
| Author(s) : Cornet M , Callaerts A , Jorritsma U , Bolt H , Vercruysse A , Rogiers V |
| Ref : Chemical Research in Toxicology , 8 :987 , 1995 |
| Abstract : |
| PubMedSearch : Cornet_1995_Chem.Res.Toxicol_8_987 |
| PubMedID: 8555415 |