Triclabendazole-sulfoxide

Triclabendazole (TCBZ) is an anthelmintic used to treat fascioliasis in animals and humans. TCBZ-resistant strains in F. hepatica appeared

General

Type : Benzimidazole, Sulfur Compound, Organochlorine, Anthelmintic

Chemical_Nomenclature :

Canonical SMILES :

InChI :

InChIKey :

Other name(s) : Triclabendazole sulfoxide  ||  6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfinyl)-1H-benzo[d]imidazole  ||  6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfinyl-1H-benzimidazole  ||  1H-Benzimidazole, 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfinyl)-  ||  TCBZSOX  ||  TCBZSX  ||  TCBZ-SOX  ||  TCBZ-SX


MW : 375.7

Formula : C14H9Cl3N2O2S

CAS_number : 100648-13-3

PubChem : 127657

UniChem :

Target

Structures : No structure

Families : Carb_B_Platyhelminthe

References (2)

Title : Fasciolosis, a foodborne zoonotic trematode infection in cattle in Bangladesh: multifaceted validation of parthenogenecity and anthelmintic efficacy - Ali_2026_Parasite_33_7
Author(s) : Ali H , Hossain S , Labony SS , Islam A , Hasan MM , Dey AR , Alam M , Khan A , Alim A , Anisuzzaman
Ref : Parasite , 33 :7 , 2026
Abstract :
PubMedSearch : Ali_2026_Parasite_33_7
PubMedID: 41670223
Gene_locus related to this paper: fashe-a0a4e0s0j7

Title : A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in Fasciola hepatica Carboxylesterase B - Miranda-Miranda_2022_Genes.(Basel)_13_
Author(s) : Miranda-Miranda E , Scarcella S , Reynaud E , Narvaez-Padilla V , Neira G , Mera YSR , Aguilar-Diaz H , Cossio-Bayugar R
Ref : Genes (Basel) , 13 : , 2022
Abstract :
PubMedSearch : Miranda-Miranda_2022_Genes.(Basel)_13_
PubMedID: 36292784
Gene_locus related to this paper: fashe-a0a4e0s0j7