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Substrate Report for: 4-MOMMP

Turnover 10 times lower than the model general esterase substrate CMNA. Its strong chemical stability allows to quantify low picogram levels of hCE1 when using an endpoint measurement over 24 hours. Its turnover by hCE1 is at least 10-fold more selective compared to 13 different serine hydrolases tested and 40- to 50-fold more selective compared to hCE2



General
Type: Pyridine
Chemical_Nomenclature: N-(6-methoxy-2-methylpyridin-3-yl)-4-methyloctanamide
Canonical SMILES:
InChI:
InChIKey:
Other name(s):
MW: 278,3
Formula: C16H26N2O2
CAS_number:
PubChem:
UniChem:
IUPHAR:
Wikipedia:

Target families
4-MOMMP ligand of proteins in family: Carb_B_Chordata
No structure

Protein target
Enzyme: human-CES1

References
Search PubMed for references concerning: 4-MOMMP
    Title: Development of amide-based fluorescent probes for selective measurement of carboxylesterase 1 activity in tissue extracts
    Kodani SD, Barthelemy M, Kamita SG, Hammock B, Morisseau C
    Ref: Analytical Biochemistry, 539:81, 2017 : PubMed