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Substrate Report for: Lysylphosphatidylglycerol

Specific aminoacylation of the phospholipid phosphatidylglycerol (PG) with alanine (or with lysine) was shown to render various bacteria less susceptible to antimicrobial agents and environmental stresses


General
Type Hexanoate, Alkyl ester, Phosphatidylglycerol
Chemical_Nomenclature [2,3-dihydroxypropoxy(hydroxy)phosphoryl] (2S)-2,6-diaminohexanoate
Canonical SMILES C(CCN)CC(C(=O)OP(=O)(O)OCC(CO)O)N
InChI InChI=1S/C9H21N2O7P/c10-4-2-1-3-8(11)9(14)18-19(15,16)17-6-7(13)5-12/h7-8,12-13H,1-6,10-11H2,(H,15,16)/t7?,8-/m0/s1
InChIKey FGYYWCMRFGLJOB-MQWKRIRWSA-N
Other name(s) lysyl-phosphatidylglycerol ; (S)-2,6-diaminohexanoic (2,3-dihydroxypropyl phosphoric) anhydride ; L-Lysine, monoanhydride with 2,3-dihydroxypropyl dihydrogen phosphate
________________________________________________________________________________________________
MW|300.25
Formula|C9H21N2O7P
CAS_number|42241-11-2
PubChem|6451847
UniChem|FGYYWCMRFGLJOB-MQWKRIRWSA-N
IUPHAR|
Wikipedia|

Target
Families | Lysylphosphatidylglycerol ligand of proteins in family: 6_AlphaBeta_hydrolase
Protein | entfc-q3xx25

References:
Search PubMed for references concerning: Lysylphosphatidylglycerol
    Title: A conserved hydrolase responsible for the cleavage of aminoacylphosphatidylglycerol in the membrane of Enterococcus faecium
    Smith AM, Harrison JS, Sprague KM, Roy H
    Ref: Journal of Biological Chemistry, 288:22768, 2013 : PubMed