Vixotrigine
General
Type : Pro-Drug || Drug || Not A\/B H target || Pyrrolidine || Crboxamide
Chemical_Nomenclature : (2S,5R)-5-[4-[(2-fluorophenyl)methoxy]phenyl]pyrrolidine-2-carboxamide
Canonical SMILES : C1CC(NC1C2=CC=C(C=C2)OCC3=CC=CC=C3F)C(=O)N
InChI : InChI=1S\/C18H19FN2O2\/c19-15-4-2-1-3-13(15)11-23-14-7-5-12(6-8-14)16-9-10-17(21-16)18(20)22\/h1-8,16-17,21H,9-11H2,(H2,20,22)\/t16-,17+\/m1\/s1
InChIKey : JESCETIFNOFKEU-SJORKVTESA-N
Other name(s) : Raxatrigine, CNV-1014802, CNV1014802, SCHEMBL310473, CHEMBL3544913, DB11706
Target
Families : Carb_B_Chordata
References (1)
| Title : Optimal pH 8.5 to 9 for the Hydrolysis of Vixotrigine and Other Basic Substrates of Carboxylesterase-1 in Human Liver Microsomes - Johnson_2022_Xenobiotica_52_105 |
| Author(s) : Johnson JL , Huang J , Rooney M , Gu C |
| Ref : Xenobiotica , 52 :105 , 2021 |
| Abstract : Johnson_2022_Xenobiotica_52_105 |
| ESTHER : Johnson_2022_Xenobiotica_52_105 |
| PubMedSearch : Johnson_2022_Xenobiotica_52_105 |
| PubMedID: 34904522 |