Tetrazoles are a class of synthetic organic heterocyclic compound, consisting of a 5-member ring of four nitrogen atoms and one carbon atom. Tetrazoles can act as bioisosteres for carboxylate groups because they have similar pKa and are deprotonated at physiological pH. Building block for many substrates of enzymes
Substrate Main targeted enzyme families Type Structure
Olmesartan-medoxomil CMBL Not A\/B H target Tetrazol