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Sin-Gly-Pro

General

Type : Peptide,Pyrrolidine

Chemical_Nomenclature : (2S)-1-[2-(3-carboxypropanoylamino)acetyl]pyrrolidine-2-carboxylic acid

Canonical SMILES : C1CC(N(C1)C(=O)CNC(=O)CCC(=O)O)C(=O)O

InChI : InChI=1S\/C11H16N2O6\/c14-8(3-4-10(16)17)12-6-9(15)13-5-1-2-7(13)11(18)19\/h7H,1-6H2,(H,12,14)(H,16,17)(H,18,19)\/t7-\/m0\/s1

InChIKey : KIGCMCPBYVQRAD-ZETCQYMHSA-N

Other name(s) : AC1NRD6M,(2S)-1-[2-[(4-hydroxy-4-oxobutanoyl)amino]acetyl]pyrrolidine-2-carboxylic acid

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MW : 272.25

Formula : C11H16N2O6

CAS_number :

PubChem : 5289375

UniChem : KIGCMCPBYVQRAD-ZETCQYMHSA-N

Target

Families : Sin-Gly-Pro ligand of proteins in family
S9N_PPCE_Peptidase_S9

Protein :
pig-ppce

References (2)

1. Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site

Title : Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site - Szeltner_2002_J.Biol.Chem_277_42613

Author(s) : Szeltner Z , Rea D , Renner V , Fulop V , Polgar L

Ref : Journal of Biological Chemistry , 277 :42613 , 2002

Abstract : Szeltner_2002_J.Biol.Chem_277_42613

ESTHER : Szeltner_2002_J.Biol.Chem_277_42613

PubMedSearch : Szeltner_2002_J.Biol.Chem_277_42613

PubMedID: 12202494

Gene_locus related to this paper: pig-ppce

2. Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase

Title : Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase - Szeltner_2002_J.Biol.Chem_277_44597

Author(s) : Szeltner Z , Rea D , Juhasz T , Renner V , Mucsi Z , Orosz G , Fulop V , Polgar L

Ref : Journal of Biological Chemistry , 277 :44597 , 2002

Abstract : Szeltner_2002_J.Biol.Chem_277_44597

ESTHER : Szeltner_2002_J.Biol.Chem_277_44597

PubMedSearch : Szeltner_2002_J.Biol.Chem_277_44597

PubMedID: 12228249

Gene_locus related to this paper: pig-ppce

Array
(
    [id] => 4104
    [inhibitor] => Sin-Gly-Pro
    [type] => Array
        (
            [0] => Peptide
            [1] => Pyrrolidine
        )

    [other_name] => Array
        (
            [0] => AC1NRD6M
            [1] => (2S)-1-[2-[(4-hydroxy-4-oxobutanoyl)amino]acetyl]pyrrolidine-2-carboxylic acid
        )

    [chemical_nomenclature] => (2S)-1-[2-(3-carboxypropanoylamino)acetyl]pyrrolidine-2-carboxylic acid
    [formula] => C11H16N2O6
    [cas_number] => 
    [mw] => 272.25
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Szeltner_2002_J.Biol.Chem_277_42613 || Szeltner_2002_J.Biol.Chem_277_44597
    [comment] => 
    [gene_locus] => pig-ppce
    [kin_inhibitor] => 
    [cid] => 5289375
    [family] => S9N_PPCE_Peptidase_S9
    [inchikey] => KIGCMCPBYVQRAD-ZETCQYMHSA-N
    [canonicalsmiles] => C1CC(N(C1)C(=O)CNC(=O)CCC(=O)O)C(=O)O
    [inchi] => InChI=1S\/C11H16N2O6\/c14-8(3-4-10(16)17)12-6-9(15)13-5-1-2-7(13)11(18)19\/h7H,1-6H2,(H,12,14)(H,16,17)(H,18,19)\/t7-\/m0\/s1
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)