Title : A self-compartmentalizing hexamer serine protease from Pyrococcus horikoshii: substrate selection achieved through multimerization - Menyhard_2013_J.Biol.Chem_288_17884 |
Author(s) : Menyhard DK , Kiss-Szeman AJ , Tichy-Racs E , Hornung B , Radi K , Szeltner Z , Domokos K , Szamosi I , Naray-Szabo G , Polgar L , Harmat V |
Ref : Journal of Biological Chemistry , 288 :17884 , 2013 |
Abstract : |
PubMedSearch : Menyhard_2013_J.Biol.Chem_288_17884 |
PubMedID: 23632025 |
Gene_locus related to this paper: pyrho-PH0594 |
Title : The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity - Szeltner_2012_Biochim.Biophys.Acta_1834_98 |
Author(s) : Szeltner Z , Juhasz T , Szamosi I , Rea D , Fulop V , Modos K , Juliano L , Polgar L |
Ref : Biochimica & Biophysica Acta , 1834 :98 , 2012 |
Abstract : |
PubMedSearch : Szeltner_2012_Biochim.Biophys.Acta_1834_98 |
PubMedID: 22940581 |
Gene_locus related to this paper: pig-ppce |
Title : Structure and catalysis of acylaminoacyl peptidase: closed and open subunits of a dimer oligopeptidase - Harmat_2011_J.Biol.Chem_286_1987 |
Author(s) : Harmat V , Domokos K , Menyhard DK , Pallo A , Szeltner Z , Szamosi I , Beke-Somfai T , Naray-Szabo G , Polgar L |
Ref : Journal of Biological Chemistry , 286 :1987 , 2011 |
Abstract : |
PubMedSearch : Harmat_2011_J.Biol.Chem_286_1987 |
PubMedID: 21084296 |
Gene_locus related to this paper: aerpe-APE1547 |
Title : GAP43 shows partial co-localisation but no strong physical interaction with prolyl oligopeptidase - Szeltner_2010_Biochim.Biophys.Acta_1804_2162 |
Author(s) : Szeltner Z , Morawski M , Juhasz T , Szamosi I , Liliom K , Csizmok V , Tolgyesi F , Polgar L |
Ref : Biochimica & Biophysica Acta , 1804 :2162 , 2010 |
Abstract : |
PubMedSearch : Szeltner_2010_Biochim.Biophys.Acta_1804_2162 |
PubMedID: 20869470 |
Title : Characterization of a novel acylaminoacyl peptidase with hexameric structure and endopeptidase activity - Szeltner_2009_Biochim.Biophys.Acta_1794_1204 |
Author(s) : Szeltner Z , Kiss AL , Domokos K , Harmat V , Naray-Szabo G , Polgar L |
Ref : Biochimica & Biophysica Acta , 1794 :1204 , 2009 |
Abstract : |
PubMedSearch : Szeltner_2009_Biochim.Biophys.Acta_1794_1204 |
PubMedID: 19303951 |
Gene_locus related to this paper: pyrho-PH0594 |
Title : Structure, function and biological relevance of prolyl oligopeptidase - Szeltner_2008_Curr.Protein.Pept.Sci_9_96 |
Author(s) : Szeltner Z , Polgar L |
Ref : Curr Protein Pept Sci , 9 :96 , 2008 |
Abstract : |
PubMedSearch : Szeltner_2008_Curr.Protein.Pept.Sci_9_96 |
PubMedID: 18336325 |
Title : Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase - Kiss_2008_J.Struct.Biol_162_312 |
Author(s) : Kiss AL , Pallo A , Naray-Szabo G , Harmat V , Polgar L |
Ref : J Struct Biol , 162 :312 , 2008 |
Abstract : |
PubMedSearch : Kiss_2008_J.Struct.Biol_162_312 |
PubMedID: 18325786 |
Gene_locus related to this paper: aerpe-APE1547 |
Title : Fluorescence resonance energy transfer (FRET) peptides and cycloretro-inverso peptides derived from bradykinin as substrates and inhibitors of prolyl oligopeptidase - Gorrao_2007_Peptides_28_2146 |
Author(s) : Gorrao SS , Hemerly JP , Lima AR , Melo RL , Szeltner Z , Polgar L , Juliano MA , Juliano L |
Ref : Peptides , 28 :2146 , 2007 |
Abstract : |
PubMedSearch : Gorrao_2007_Peptides_28_2146 |
PubMedID: 17904692 |
Title : The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity - Kiss_2007_J.Mol.Biol_368_509 |
Author(s) : Kiss AL , Hornung B , Radi K , Gengeliczki Z , Sztaray B , Juhasz T , Szeltner Z , Harmat V , Polgar L |
Ref : Journal of Molecular Biology , 368 :509 , 2007 |
Abstract : |
PubMedSearch : Kiss_2007_J.Mol.Biol_368_509 |
PubMedID: 17350041 |
Gene_locus related to this paper: aerpe-APE1547 |
Title : Truncated prolyl oligopeptidase from Pyrococcus furiosus - Juhasz_2007_Proteins_69_633 |
Author(s) : Juhasz T , Szeltner Z , Polgar L |
Ref : Proteins , 69 :633 , 2007 |
Abstract : |
PubMedSearch : Juhasz_2007_Proteins_69_633 |
PubMedID: 17623862 |
Title : Properties of the prolyl oligopeptidase homologue from Pyrococcus furiosus - Juhasz_2006_FEBS.Lett_580_3493 |
Author(s) : Juhasz T , Szeltner Z , Polgar L |
Ref : FEBS Letters , 580 :3493 , 2006 |
Abstract : |
PubMedSearch : Juhasz_2006_FEBS.Lett_580_3493 |
PubMedID: 16714022 |
Title : The PREPL A protein, a new member of the prolyl oligopeptidase family, lacking catalytic activity - Szeltner_2005_Cell.Mol.Life.Sci_62_2376 |
Author(s) : Szeltner Z , Alshafee I , Juhasz T , Parvari R , Polgar L |
Ref : Cell Mol Life Sciences , 62 :2376 , 2005 |
Abstract : |
PubMedSearch : Szeltner_2005_Cell.Mol.Life.Sci_62_2376 |
PubMedID: 16143824 |
Gene_locus related to this paper: human-PREPL |
Title : Flexibility of prolyl oligopeptidase: molecular dynamics and molecular framework analysis of the potential substrate pathways - Fuxreiter_2005_Proteins_60_504 |
Author(s) : Fuxreiter M , Magyar C , Juhasz T , Szeltner Z , Polgar L , Simon I |
Ref : Proteins , 60 :504 , 2005 |
Abstract : |
PubMedSearch : Fuxreiter_2005_Proteins_60_504 |
PubMedID: 15971204 |
Title : Unclosed beta-propellers display stable structures: implications for substrate access to the active site of prolyl oligopeptidase - Juhasz_2005_J.Mol.Biol_346_907 |
Author(s) : Juhasz T , Szeltner Z , Fulop V , Polgar L |
Ref : Journal of Molecular Biology , 346 :907 , 2005 |
Abstract : |
PubMedSearch : Juhasz_2005_J.Mol.Biol_346_907 |
PubMedID: 15713471 |
Title : Crystallization and preliminary crystallographic analysis of porcine acylaminoacyl peptidase - Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942 |
Author(s) : Wright H , Kiss AL , Szeltner Z , Polgar L , Fulop V |
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 61 :942 , 2005 |
Abstract : |
PubMedSearch : Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942 |
PubMedID: 16511202 |
Gene_locus related to this paper: aerpe-APE1547 |
Title : Concerted structural changes in the peptidase and the propeller domains of prolyl oligopeptidase are required for substrate binding - Szeltner_2004_J.Mol.Biol_340_627 |
Author(s) : Szeltner Z , Rea D , Juhasz T , Renner V , Fulop V , Polgar L |
Ref : Journal of Molecular Biology , 340 :627 , 2004 |
Abstract : |
PubMedSearch : Szeltner_2004_J.Mol.Biol_340_627 |
PubMedID: 15210359 |
Gene_locus related to this paper: pig-q6q2c2 |
Title : Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate binding - Szeltner_2003_J.Biol.Chem_278_48786 |
Author(s) : Szeltner Z , Rea D , Renner V , Juliano L , Fulop V , Polgar L |
Ref : Journal of Biological Chemistry , 278 :48786 , 2003 |
Abstract : |
PubMedSearch : Szeltner_2003_J.Biol.Chem_278_48786 |
PubMedID: 14514675 |
Gene_locus related to this paper: pig-ppce |
Title : Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site - Szeltner_2002_J.Biol.Chem_277_42613 |
Author(s) : Szeltner Z , Rea D , Renner V , Fulop V , Polgar L |
Ref : Journal of Biological Chemistry , 277 :42613 , 2002 |
Abstract : |
PubMedSearch : Szeltner_2002_J.Biol.Chem_277_42613 |
PubMedID: 12202494 |
Gene_locus related to this paper: pig-ppce |
Title : Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase - Szeltner_2002_J.Biol.Chem_277_44597 |
Author(s) : Szeltner Z , Rea D , Juhasz T , Renner V , Mucsi Z , Orosz G , Fulop V , Polgar L |
Ref : Journal of Biological Chemistry , 277 :44597 , 2002 |
Abstract : |
PubMedSearch : Szeltner_2002_J.Biol.Chem_277_44597 |
PubMedID: 12228249 |
Gene_locus related to this paper: pig-ppce |
Title : The prolyl oligopeptidase family - Polgar_2002_Cell.Mol.Life.Sci_59_349 |
Author(s) : Polgar L |
Ref : Cell Mol Life Sciences , 59 :349 , 2002 |
Abstract : |
PubMedSearch : Polgar_2002_Cell.Mol.Life.Sci_59_349 |
PubMedID: 11915948 |
Title : Structures of prolyl oligopeptidase substrate\/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue - Fulop_2001_J.Biol.Chem_276_1262 |
Author(s) : Fulop V , Szeltner Z , Renner V , Polgar L |
Ref : Journal of Biological Chemistry , 276 :1262 , 2001 |
Abstract : |
PubMedSearch : Fulop_2001_J.Biol.Chem_276_1262 |
PubMedID: 11031266 |
Gene_locus related to this paper: pig-ppce |
Title : The noncatalytic beta-propeller domain of prolyl oligopeptidase enhances the catalytic capability of the peptidase domain - Szeltner_2000_J.Biol.Chem_275_15000 |
Author(s) : Szeltner Z , Renner V , Polgar L |
Ref : Journal of Biological Chemistry , 275 :15000 , 2000 |
Abstract : |
PubMedSearch : Szeltner_2000_J.Biol.Chem_275_15000 |
PubMedID: 10747969 |
Title : Catalysis of serine oligopeptidases is controlled by a gating filter mechanism - Fulop_2000_EMBO.Rep_1_277 |
Author(s) : Fulop V , Szeltner Z , Polgar L |
Ref : EMBO Rep , 1 :277 , 2000 |
Abstract : |
PubMedSearch : Fulop_2000_EMBO.Rep_1_277 |
PubMedID: 11256612 |
Gene_locus related to this paper: pig-ppce |
Title : Prolyl oligopeptidase: an unusual beta-propeller domain regulates proteolysis - Fulop_1998_Cell_94_161 |
Author(s) : Fulop V , Bocskei Z , Polgar L |
Ref : Cell , 94 :161 , 1998 |
Abstract : |
PubMedSearch : Fulop_1998_Cell_94_161 |
PubMedID: 9695945 |
Gene_locus related to this paper: pig-ppce |
Title : Low barrier hydrogen bond is absent in the catalytic triads in the ground state but Is present in a transition-state complex in the prolyl oligopeptidase family of serine proteases - Kahyaoglu_1997_J.Biol.Chem_272_25547 |
Author(s) : Kahyaoglu A , Haghjoo K , Guo F , Jordan F , Kettner C , Felfoldi F , Polgar L |
Ref : Journal of Biological Chemistry , 272 :25547 , 1997 |
Abstract : |
PubMedSearch : Kahyaoglu_1997_J.Biol.Chem_272_25547 |
PubMedID: 9325271 |
Title : Effects of ionic strength on the catalysis and stability of prolyl oligopeptidase - Polgar_1995_Biochem.J_312_267 |
Author(s) : Polgar L |
Ref : Biochemical Journal , 312 :267 , 1995 |
Abstract : |
PubMedSearch : Polgar_1995_Biochem.J_312_267 |
PubMedID: 7492323 |
Title : Prolyl oligopeptidases - Polgar_1994_Methods.Enzymol_244_188 |
Author(s) : Polgar L |
Ref : Methods Enzymol , 244 :188 , 1994 |
Abstract : |
PubMedSearch : Polgar_1994_Methods.Enzymol_244_188 |
PubMedID: 7845207 |
Title : Structural relationship between lipases and peptidases of the prolyl oligopeptidase family - Polgar_1992_FEBS.Lett_311_281 |
Author(s) : Polgar L |
Ref : FEBS Letters , 311 :281 , 1992 |
Abstract : |
PubMedSearch : Polgar_1992_FEBS.Lett_311_281 |
PubMedID: 1397329 |
Title : A new family of serine-type peptidases related to prolyl oligopeptidase [letter] - Rawlings_1991_Biochem.J_279_907 |
Author(s) : Rawlings ND , Polgar L , Barrett AJ |
Ref : Biochemical Journal , 279 :907 , 1991 |
Abstract : |
PubMedSearch : Rawlings_1991_Biochem.J_279_907 |
PubMedID: 1953688 |