Amit T

General

Full name : Amit Tamar

First name : Tamar

Mail : Department of Pharmacology, Technion- Faculty of Medicine, P.O.B. 9697, 31096 Haifa

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Country : Israel

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References (19)

Title : Design, synthesis and evaluation of novel dual monoamine-cholinesterase inhibitors as potential treatment for Alzheimer's disease - Liu_2016_Neuropharmacol_109_376
Author(s) : Liu W , Lang M , Youdim MB , Amit T , Sun Y , Zhang Z , Wang Y , Weinreb O
Ref : Neuropharmacology , 109 :376 , 2016
Abstract :
PubMedSearch : Liu_2016_Neuropharmacol_109_376
PubMedID: 27318273

Title : Neuroprotective effects of multifaceted hybrid agents targeting MAO, cholinesterase, iron and beta-amyloid in ageing and Alzheimer's disease - Weinreb_2016_Br.J.Pharmacol_173_2080
Author(s) : Weinreb O , Amit T , Bar-Am O , Youdim MB
Ref : British Journal of Pharmacology , 173 :2080 , 2016
Abstract :
PubMedSearch : Weinreb_2016_Br.J.Pharmacol_173_2080
PubMedID: 26332830

Title : From anti-Parkinson's drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer's disease - Zheng_2012_J.Alzheimers.Dis_30_1
Author(s) : Zheng H , Amit T , Bar-Am O , Fridkin M , Youdim MB , Mandel SA
Ref : J Alzheimers Dis , 30 :1 , 2012
Abstract :
PubMedSearch : Zheng_2012_J.Alzheimers.Dis_30_1
PubMedID: 22387411

Title : Ladostigil: a novel multimodal neuroprotective drug with cholinesterase and brain-selective monoamine oxidase inhibitory activities for Alzheimer's disease treatment - Weinreb_2012_Curr.Drug.Targets_13_483
Author(s) : Weinreb O , Amit T , Bar-Am O , Youdim MB
Ref : Curr Drug Targets , 13 :483 , 2012
Abstract :
PubMedSearch : Weinreb_2012_Curr.Drug.Targets_13_483
PubMedID: 22280345

Title : A novel anti-Alzheimer's disease drug, ladostigil neuroprotective, multimodal brain-selective monoamine oxidase and cholinesterase inhibitor - Weinreb_2011_Int.Rev.Neurobiol_100_191
Author(s) : Weinreb O , Amit T , Bar-Am O , Youdim MB
Ref : International Review of Neurobiology , 100 :191 , 2011
Abstract :
PubMedSearch : Weinreb_2011_Int.Rev.Neurobiol_100_191
PubMedID: 21971009

Title : Propargylamine containing compounds as modulators of proteolytic cleavage of amyloid-beta protein precursor: involvement of MAPK and PKC activation - Bar-Am_2010_J.Alzheimers.Dis_21_361
Author(s) : Bar-Am O , Amit T , Weinreb O , Youdim MB , Mandel S
Ref : J Alzheimers Dis , 21 :361 , 2010
Abstract :
PubMedSearch : Bar-Am_2010_J.Alzheimers.Dis_21_361
PubMedID: 20555137

Title : The novel cholinesterase-monoamine oxidase inhibitor and antioxidant, ladostigil, confers neuroprotection in neuroblastoma cells and aged rats - Bar-Am_2009_J.Mol.Neurosci_37_135
Author(s) : Bar-Am O , Weinreb O , Amit T , Youdim MB
Ref : Journal of Molecular Neuroscience , 37 :135 , 2009
Abstract :
PubMedSearch : Bar-Am_2009_J.Mol.Neurosci_37_135
PubMedID: 18751929

Title : Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs - Weinreb_2009_Neurotherapeutics_6_163
Author(s) : Weinreb O , Mandel S , Bar-Am O , Yogev-Falach M , Avramovich-Tirosh Y , Amit T , Youdim MB
Ref : Neurotherapeutics , 6 :163 , 2009
Abstract :
PubMedSearch : Weinreb_2009_Neurotherapeutics_6_163
PubMedID: 19110207

Title : The neuroprotective mechanism of action of the multimodal drug ladostigil - Weinreb_2008_Front.Biosci_13_5131
Author(s) : Weinreb O , Amit T , Bar-Am O , Yogev-Falach M , Youdim MB
Ref : Front Biosci , 13 :5131 , 2008
Abstract :
PubMedSearch : Weinreb_2008_Front.Biosci_13_5131
PubMedID: 18508575

Title : The neuroprotective effect of ladostigil against hydrogen peroxide-mediated cytotoxicity - Weinreb_2008_Chem.Biol.Interact_175_318
Author(s) : Weinreb O , Bar-Am O , Amit T , Drigues N , Sagi Y , Youdim MB
Ref : Chemico-Biological Interactions , 175 :318 , 2008
Abstract :
PubMedSearch : Weinreb_2008_Chem.Biol.Interact_175_318
PubMedID: 18598687

Title : Aminoindan and hydroxyaminoindan, metabolites of rasagiline and ladostigil, respectively, exert neuroprotective properties in vitro - Bar-Am_2007_J.Neurochem_103_500
Author(s) : Bar-Am O , Amit T , Youdim MB
Ref : Journal of Neurochemistry , 103 :500 , 2007
Abstract :
PubMedSearch : Bar-Am_2007_J.Neurochem_103_500
PubMedID: 17635668

Title : A multifunctional, neuroprotective drug, ladostigil (TV3326), regulates holo-APP translation and processing - Yogev-Falach_2006_FASEB.J_20_2177
Author(s) : Yogev-Falach M , Bar-Am O , Amit T , Weinreb O , Youdim MB
Ref : FASEB Journal , 20 :2177 , 2006
Abstract :
PubMedSearch : Yogev-Falach_2006_FASEB.J_20_2177
PubMedID: 16935943

Title : Implications of co-morbidity for etiology and treatment of neurodegenerative diseases with multifunctional neuroprotective-neurorescue drugs\; ladostigil - Youdim_2006_Neurotox.Res_10_181
Author(s) : Youdim MB , Amit T , Bar-Am O , Weinreb O , Yogev-Falach M
Ref : Neurotox Res , 10 :181 , 2006
Abstract :
PubMedSearch : Youdim_2006_Neurotox.Res_10_181
PubMedID: 17197368

Title : Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition - Youdim_2005_J.Neurosci.Res_79_172
Author(s) : Youdim MB , Bar Am O , Yogev-Falach M , Weinreb O , Maruyama W , Naoi M , Amit T
Ref : Journal of Neuroscience Research , 79 :172 , 2005
Abstract :
PubMedSearch : Youdim_2005_J.Neurosci.Res_79_172
PubMedID: 15573406

Title : Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo - Bar-Am_2004_J.Neurochem_89_1119
Author(s) : Bar-Am O , Yogev-Falach M , Amit T , Sagi Y , Youdim MB
Ref : Journal of Neurochemistry , 89 :1119 , 2004
Abstract :
PubMedSearch : Bar-Am_2004_J.Neurochem_89_1119
PubMedID: 15147504

Title : Poster (57) A novel neuroprotective trifunctional cholinesterase inhibitor derivative of the antiparkinson drug, rasagiline, for treatment of dementia and lewy body disease co-morbid with depression -
Author(s) : Youdim MB , Sagi Y , Derigus N , Naoi M , Maruyama W , Amit T , Falash-Yogev M , Weinstock M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :351 , 2004
PubMedID:

Title : PKC and MAP kinase-dependent processing of amyloid precursor protein (APP) by neuroprotective propargylamine cholinesterase inhibitors derived from rasagiline and nonsteroidal anti-inflammatory drugs. -
Author(s) : Youdim MB , Amit T , Avramovich Y , Bar-Am O , Weinstock M , Yogev-Falach M
Ref : Cholinergic Mechanisms, CRC Press :353 , 2004
PubMedID:

Title : Amyloid Processing and Signal Transduction Properties of Antiparkinson-Antialzheimer Neuroprotective Drugs Rasagiline and TV3326 - Youdim_2003_Ann.N.Y.Acad.Sci_993_378
Author(s) : Youdim MB , Amit T , Bar-Am O , Weinstock M , Yogev-Falach M
Ref : Annals of the New York Academy of Sciences , 993 :378 , 2003
Abstract :
PubMedSearch : Youdim_2003_Ann.N.Y.Acad.Sci_993_378
PubMedID: 12853332

Title : The involvement of mitogen-activated protein (MAP) kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline - Yogev-Falach_2002_Faseb.J_16_1674
Author(s) : Yogev-Falach M , Amit T , Bar-Am O , Weinstock M , Youdim MB
Ref : FASEB Journal , 16 :1674 , 2002
Abstract :
PubMedSearch : Yogev-Falach_2002_Faseb.J_16_1674
PubMedID: 12206996