Title : Neuroprotective effects of multifaceted hybrid agents targeting MAO, cholinesterase, iron and beta-amyloid in ageing and Alzheimer's disease - Weinreb_2016_Br.J.Pharmacol_173_2080 |
Author(s) : Weinreb O , Amit T , Bar-Am O , Youdim MB |
Ref : British Journal of Pharmacology , 173 :2080 , 2016 |
Abstract : |
PubMedSearch : Weinreb_2016_Br.J.Pharmacol_173_2080 |
PubMedID: 26332830 |
Title : Ladostigil: a novel multimodal neuroprotective drug with cholinesterase and brain-selective monoamine oxidase inhibitory activities for Alzheimer's disease treatment - Weinreb_2012_Curr.Drug.Targets_13_483 |
Author(s) : Weinreb O , Amit T , Bar-Am O , Youdim MB |
Ref : Curr Drug Targets , 13 :483 , 2012 |
Abstract : |
PubMedSearch : Weinreb_2012_Curr.Drug.Targets_13_483 |
PubMedID: 22280345 |
Title : From anti-Parkinson's drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer's disease - Zheng_2012_J.Alzheimers.Dis_30_1 |
Author(s) : Zheng H , Amit T , Bar-Am O , Fridkin M , Youdim MB , Mandel SA |
Ref : J Alzheimers Dis , 30 :1 , 2012 |
Abstract : |
PubMedSearch : Zheng_2012_J.Alzheimers.Dis_30_1 |
PubMedID: 22387411 |
Title : A novel anti-Alzheimer's disease drug, ladostigil neuroprotective, multimodal brain-selective monoamine oxidase and cholinesterase inhibitor - Weinreb_2011_Int.Rev.Neurobiol_100_191 |
Author(s) : Weinreb O , Amit T , Bar-Am O , Youdim MB |
Ref : International Review of Neurobiology , 100 :191 , 2011 |
Abstract : |
PubMedSearch : Weinreb_2011_Int.Rev.Neurobiol_100_191 |
PubMedID: 21971009 |
Title : Propargylamine containing compounds as modulators of proteolytic cleavage of amyloid-beta protein precursor: involvement of MAPK and PKC activation - Bar-Am_2010_J.Alzheimers.Dis_21_361 |
Author(s) : Bar-Am O , Amit T , Weinreb O , Youdim MB , Mandel S |
Ref : J Alzheimers Dis , 21 :361 , 2010 |
Abstract : |
PubMedSearch : Bar-Am_2010_J.Alzheimers.Dis_21_361 |
PubMedID: 20555137 |
Title : The novel cholinesterase-monoamine oxidase inhibitor and antioxidant, ladostigil, confers neuroprotection in neuroblastoma cells and aged rats - Bar-Am_2009_J.Mol.Neurosci_37_135 |
Author(s) : Bar-Am O , Weinreb O , Amit T , Youdim MB |
Ref : Journal of Molecular Neuroscience , 37 :135 , 2009 |
Abstract : |
PubMedSearch : Bar-Am_2009_J.Mol.Neurosci_37_135 |
PubMedID: 18751929 |
Title : Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs - Weinreb_2009_Neurotherapeutics_6_163 |
Author(s) : Weinreb O , Mandel S , Bar-Am O , Yogev-Falach M , Avramovich-Tirosh Y , Amit T , Youdim MB |
Ref : Neurotherapeutics , 6 :163 , 2009 |
Abstract : |
PubMedSearch : Weinreb_2009_Neurotherapeutics_6_163 |
PubMedID: 19110207 |
Title : The neuroprotective mechanism of action of the multimodal drug ladostigil - Weinreb_2008_Front.Biosci_13_5131 |
Author(s) : Weinreb O , Amit T , Bar-Am O , Yogev-Falach M , Youdim MB |
Ref : Front Biosci , 13 :5131 , 2008 |
Abstract : |
PubMedSearch : Weinreb_2008_Front.Biosci_13_5131 |
PubMedID: 18508575 |
Title : The neuroprotective effect of ladostigil against hydrogen peroxide-mediated cytotoxicity - Weinreb_2008_Chem.Biol.Interact_175_318 |
Author(s) : Weinreb O , Bar-Am O , Amit T , Drigues N , Sagi Y , Youdim MB |
Ref : Chemico-Biological Interactions , 175 :318 , 2008 |
Abstract : |
PubMedSearch : Weinreb_2008_Chem.Biol.Interact_175_318 |
PubMedID: 18598687 |
Title : Aminoindan and hydroxyaminoindan, metabolites of rasagiline and ladostigil, respectively, exert neuroprotective properties in vitro - Bar-Am_2007_J.Neurochem_103_500 |
Author(s) : Bar-Am O , Amit T , Youdim MB |
Ref : Journal of Neurochemistry , 103 :500 , 2007 |
Abstract : |
PubMedSearch : Bar-Am_2007_J.Neurochem_103_500 |
PubMedID: 17635668 |
Title : A multifunctional, neuroprotective drug, ladostigil (TV3326), regulates holo-APP translation and processing - Yogev-Falach_2006_FASEB.J_20_2177 |
Author(s) : Yogev-Falach M , Bar-Am O , Amit T , Weinreb O , Youdim MB |
Ref : FASEB Journal , 20 :2177 , 2006 |
Abstract : |
PubMedSearch : Yogev-Falach_2006_FASEB.J_20_2177 |
PubMedID: 16935943 |
Title : Implications of co-morbidity for etiology and treatment of neurodegenerative diseases with multifunctional neuroprotective-neurorescue drugs\; ladostigil - Youdim_2006_Neurotox.Res_10_181 |
Author(s) : Youdim MB , Amit T , Bar-Am O , Weinreb O , Yogev-Falach M |
Ref : Neurotox Res , 10 :181 , 2006 |
Abstract : |
PubMedSearch : Youdim_2006_Neurotox.Res_10_181 |
PubMedID: 17197368 |
Title : PKC and MAP kinase-dependent processing of amyloid precursor protein (APP) by neuroprotective propargylamine cholinesterase inhibitors derived from rasagiline and nonsteroidal anti-inflammatory drugs. - |
Author(s) : Youdim MB , Amit T , Avramovich Y , Bar-Am O , Weinstock M , Yogev-Falach M |
Ref : Cholinergic Mechanisms, CRC Press :353 , 2004 |
PubMedID: |
Title : Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo - Bar-Am_2004_J.Neurochem_89_1119 |
Author(s) : Bar-Am O , Yogev-Falach M , Amit T , Sagi Y , Youdim MB |
Ref : Journal of Neurochemistry , 89 :1119 , 2004 |
Abstract : |
PubMedSearch : Bar-Am_2004_J.Neurochem_89_1119 |
PubMedID: 15147504 |
Title : Amyloid Processing and Signal Transduction Properties of Antiparkinson-Antialzheimer Neuroprotective Drugs Rasagiline and TV3326 - Youdim_2003_Ann.N.Y.Acad.Sci_993_378 |
Author(s) : Youdim MB , Amit T , Bar-Am O , Weinstock M , Yogev-Falach M |
Ref : Annals of the New York Academy of Sciences , 993 :378 , 2003 |
Abstract : |
PubMedSearch : Youdim_2003_Ann.N.Y.Acad.Sci_993_378 |
PubMedID: 12853332 |
Title : The involvement of mitogen-activated protein (MAP) kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline - Yogev-Falach_2002_Faseb.J_16_1674 |
Author(s) : Yogev-Falach M , Amit T , Bar-Am O , Weinstock M , Youdim MB |
Ref : FASEB Journal , 16 :1674 , 2002 |
Abstract : |
PubMedSearch : Yogev-Falach_2002_Faseb.J_16_1674 |
PubMedID: 12206996 |