| Title : Unveiling the molecular mechanisms and developmental consequences of mercury (Hg) toxicity in zebrafish embryo-larvae: A comprehensive approach - Henriques_2023_Neurotoxicol.Teratol__107302 |
| Author(s) : Henriques MC , Carvalho I , Santos C , Herdeiro MT , Fardilha M , Pavlaki MD , Loureiro S |
| Ref : Neurotoxicology & Teratology , :107302 , 2023 |
| Abstract : |
| PubMedSearch : Henriques_2023_Neurotoxicol.Teratol__107302 |
| PubMedID: 37739188 |
| Title : Neuroprotective Effects of Cholinesterase Inhibitors: Current Scenario in Therapies for Alzheimer's Disease and Future Perspectives - Moreira_2022_J.Alzheimers.Dis.Rep_6_177 |
| Author(s) : Moreira N , Lima J , Marchiori MF , Carvalho I , Sakamoto-Hojo ET |
| Ref : J Alzheimers Dis Rep , 6 :177 , 2022 |
| Abstract : |
| PubMedSearch : Moreira_2022_J.Alzheimers.Dis.Rep_6_177 |
| PubMedID: 35591949 |
| Title : Novel Dual AChE and ROCK2 Inhibitor Induces Neurogenesis via PTEN\/AKT Pathway in Alzheimer's Disease Model - Moreira_2022_Int.J.Mol.Sci_23_14788 |
| Author(s) : Moreira N , Tamarozzi ER , Lima J , Piassi LO , Carvalho I , Passos GA , Sakamoto-Hojo ET |
| Ref : Int J Mol Sci , 23 :14788 , 2022 |
| Abstract : |
| PubMedSearch : Moreira_2022_Int.J.Mol.Sci_23_14788 |
| PubMedID: 36499116 |
| Title : Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway - Moreira_2020_J.Alzheimers.Dis_78_353 |
| Author(s) : Moreira N , Lima J , Chierrito TPC , Carvalho I , Sakamoto-Hojo ET |
| Ref : J Alzheimers Dis , 78 :353 , 2020 |
| Abstract : |
| PubMedSearch : Moreira_2020_J.Alzheimers.Dis_78_353 |
| PubMedID: 32986667 |
| Title : Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease - de Andrade_2019_Bioorg.Med.Chem_27_931 |
| Author(s) : de Andrade P , Mantoani SP , Goncalves Nunes PS , Magadan CR , Perez C , Xavier DJ , Hojo ETS , Campillo NE , Martinez A , Carvalho I |
| Ref : Bioorganic & Medicinal Chemistry , 27 :931 , 2019 |
| Abstract : |
| PubMedSearch : de Andrade_2019_Bioorg.Med.Chem_27_931 |
| PubMedID: 30765302 |
| Title : Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors - Chierrito_2018_Eur.J.Med.Chem_145_431 |
| Author(s) : Chierrito TPC , Pedersoli-Mantoani S , Roca C , Sebastian-Perez V , Martinez-Gonzalez L , Perez DI , Perez C , Canales A , Canada FJ , Campillo NE , Carvalho I , Martinez A |
| Ref : Eur Journal of Medicinal Chemistry , 145 :431 , 2018 |
| Abstract : |
| PubMedSearch : Chierrito_2018_Eur.J.Med.Chem_145_431 |
| PubMedID: 29335209 |
| Title : From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease - Chierrito_2017_Eur.J.Med.Chem_139_773 |
| Author(s) : Chierrito TPC , Mantoani SP , Roca C , Requena C , Sebastian-Perez V , Castillo WO , Moreira NCS , Perez C , Sakamoto-Hojo ET , Takahashi CS , Jimenez-Barbero J , Canada FJ , Campillo NE , Martinez A , Carvalho I |
| Ref : Eur Journal of Medicinal Chemistry , 139 :773 , 2017 |
| Abstract : |
| PubMedSearch : Chierrito_2017_Eur.J.Med.Chem_139_773 |
| PubMedID: 28863358 |
| Title : Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors - Mantoani_2016_Molecules_21_ |
| Author(s) : Mantoani SP , Chierrito TP , Vilela AF , Cardoso CL , Martinez A , Carvalho I |
| Ref : Molecules , 21 : , 2016 |
| Abstract : |
| PubMedSearch : Mantoani_2016_Molecules_21_ |
| PubMedID: 26861273 |
| Title : In silico design and search for acetylcholinesterase inhibitors in Alzheimer's disease with a suitable pharmacokinetic profile and low toxicity - da Silva_2011_Future.Med.Chem_3_947 |
| Author(s) : da Silva VB , de Andrade P , Kawano DF , Morais PA , de Almeida JR , Carvalho I , Taft CA , da Silva CH |
| Ref : Future Med Chem , 3 :947 , 2011 |
| Abstract : |
| PubMedSearch : da Silva_2011_Future.Med.Chem_3_947 |
| PubMedID: 21707398 |
| Title : Virtual screening, molecular interaction field, molecular dynamics, docking, density functional, and ADMET properties of novel AChE inhibitors in Alzheimer's disease - da Silva_2007_J.Biomol.Struct.Dyn_24_515 |
| Author(s) : da Silva CH , Carvalho I , Taft CA |
| Ref : J Biomol Struct Dyn , 24 :515 , 2007 |
| Abstract : |
| PubMedSearch : da Silva_2007_J.Biomol.Struct.Dyn_24_515 |
| PubMedID: 17508773 |
| Title : Molecular modeling, docking and ADMET studies applied to the design of a novel hybrid for treatment of Alzheimer's disease - da Silva_2006_J.Mol.Graph.Model_25_169 |
| Author(s) : da Silva CH , Campo VL , Carvalho I , Taft CA |
| Ref : J Mol Graph Model , 25 :169 , 2006 |
| Abstract : |
| PubMedSearch : da Silva_2006_J.Mol.Graph.Model_25_169 |
| PubMedID: 16413803 |