| Title : Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer's drug candidates - Leuci_2024_Bioorg.Chem_153_107895 |
| Author(s) : Leuci R , Simic S , Carrieri A , Chaves S , La Spada G , Brunetti L , Tortorella P , Loiodice F , Laghezza A , Catto M , Santos MA , Tufarelli V , Wackerlig J , Piemontese L |
| Ref : Bioorg Chem , 153 :107895 , 2024 |
| Abstract : |
| PubMedSearch : Leuci_2024_Bioorg.Chem_153_107895 |
| PubMedID: 39454499 |
| Title : Exploiting the potential of rivastigmine-melatonin derivatives as multitarget metal-modulating drugs for neurodegenerative diseases - Dias_2024_J.Inorg.Biochem_262_112734 |
| Author(s) : Dias I , Bon L , Banas A , Chavarria D , Borges F , Guerreiro-Oliveira C , Cardoso SM , Sanna D , Garribba E , Chaves S , Santos MA |
| Ref : J Inorg Biochem , 262 :112734 , 2024 |
| Abstract : |
| PubMedSearch : Dias_2024_J.Inorg.Biochem_262_112734 |
| PubMedID: 39378762 |
| Title : New Multitarget Rivastigmine-Indole Hybrids as Potential Drug Candidates for Alzheimer's Disease - Bon_2024_Pharmaceutics_16_ |
| Author(s) : Bon L , Banas A , Dias I , Melo-Marques I , Cardoso SM , Chaves S , Santos MA |
| Ref : Pharmaceutics , 16 : , 2024 |
| Abstract : |
| PubMedSearch : Bon_2024_Pharmaceutics_16_ |
| PubMedID: 38399339 |
| Title : Rivastigmine-Benzimidazole Hybrids as Promising Multitarget Metal-Modulating Compounds for Potential Treatment of Neurodegenerative Diseases - Vicente-Zurdo_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Vicente-Zurdo D , Brunetti L , Piemontese L , Guedes B , Cardoso SM , Chavarria D , Borges F , Madrid Y , Chaves S , Santos MA |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : |
| PubMedSearch : Vicente-Zurdo_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37176018 |
| Title : Novel Rivastigmine Derivatives as Promising Multi-Target Compounds for Potential Treatment of Alzheimer's Disease - Vicente-Zurdo_2022_Biomedicines_10_1510 |
| Author(s) : Vicente-Zurdo D , Rosales-Conrado N , Leon-Gonzalez ME , Brunetti L , Piemontese L , Pereira-Santos AR , Cardoso SM , Madrid Y , Chaves S , Santos MA |
| Ref : Biomedicines , 10 :1510 , 2022 |
| Abstract : |
| PubMedSearch : Vicente-Zurdo_2022_Biomedicines_10_1510 |
| PubMedID: 35884815 |
| Title : Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease - Brunetti_2022_Eur.J.Med.Chem_237_114358 |
| Author(s) : Brunetti L , Leuci R , Carrieri A , Catto M , Occhineri S , Vinci G , Gambacorta L , Baltrukevich H , Chaves S , Laghezza A , Altomare CD , Tortorella P , Santos MA , Loiodice F , Piemontese L |
| Ref : Eur Journal of Medicinal Chemistry , 237 :114358 , 2022 |
| Abstract : |
| PubMedSearch : Brunetti_2022_Eur.J.Med.Chem_237_114358 |
| PubMedID: 35462163 |
| Title : Novel Phenothiazine\/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease - Carocci_2022_Antioxidants.(Basel)_11_ |
| Author(s) : Carocci A , Barbarossa A , Leuci R , Carrieri A , Brunetti L , Laghezza A , Catto M , Limongelli F , Chaves S , Tortorella P , Altomare CD , Santos MA , Loiodice F , Piemontese L |
| Ref : Antioxidants (Basel) , 11 : , 2022 |
| Abstract : |
| PubMedSearch : Carocci_2022_Antioxidants.(Basel)_11_ |
| PubMedID: 36139705 |
| Title : Novel Donepezil-Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer's Disease - Queda_2021_Molecules_26_ |
| Author(s) : Queda F , Cal S , Gwizdala K , Magalhaes JD , Cardoso SM , Chaves S , Piemontese L , Santos MA |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Queda_2021_Molecules_26_ |
| PubMedID: 33809771 |
| Title : Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents - Poliseno_2021_Biomolecules_11_ |
| Author(s) : Poliseno V , Chaves S , Brunetti L , Loiodice F , Carrieri A , Laghezza A , Tortorella P , Magalhaes JD , Cardoso SM , Santos MA , Piemontese L |
| Ref : Biomolecules , 11 : , 2021 |
| Abstract : |
| PubMedSearch : Poliseno_2021_Biomolecules_11_ |
| PubMedID: 33467709 |
| Title : Recent Multi-Target Approaches on the Development of Anti-Alzheimer`s Agents Integrating Metal Chelation Activity - Chaves_2021_Curr.Med.Chem__ |
| Author(s) : Chaves S , Varnagy K , Santos MA |
| Ref : Curr Med Chem , : , 2021 |
| Abstract : |
| PubMedSearch : Chaves_2021_Curr.Med.Chem__ |
| PubMedID: 33602068 |
| Title : Donepezil-based hybrids as multifunctional anti-Alzheimer's disease chelating agents: Effect of positional isomerization - Costa_2020_J.Inorg.Biochem_206_111039 |
| Author(s) : Costa M , Josselin R , Silva DF , Cardoso SM , May NV , Chaves S , Santos MA |
| Ref : J Inorg Biochem , 206 :111039 , 2020 |
| Abstract : |
| PubMedSearch : Costa_2020_J.Inorg.Biochem_206_111039 |
| PubMedID: 32171933 |
| Title : Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease - Fancellu_2020_J.Enzyme.Inhib.Med.Chem_35_211 |
| Author(s) : Fancellu G , Chand K , Tomas D , Orlandini E , Piemontese L , Silva DF , Cardoso SM , Chaves S , Santos MA |
| Ref : J Enzyme Inhib Med Chem , 35 :211 , 2020 |
| Abstract : |
| PubMedSearch : Fancellu_2020_J.Enzyme.Inhib.Med.Chem_35_211 |
| PubMedID: 31760822 |
| Title : Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds - Piemontese_2020_Molecules_25_ |
| Author(s) : Piemontese L , Sergio R , Rinaldo F , Brunetti L , Perna FM , Santos MA , Capriati V |
| Ref : Molecules , 25 : , 2020 |
| Abstract : |
| PubMedSearch : Piemontese_2020_Molecules_25_ |
| PubMedID: 32013037 |
| Title : Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease - Chaves_2020_Molecules_25_ |
| Author(s) : Chaves S , Resta S , Rinaldo F , Costa M , Josselin R , Gwizdala K , Piemontese L , Capriati V , Pereira-Santos AR , Cardoso SM , Santos MA |
| Ref : Molecules , 25 : , 2020 |
| Abstract : |
| PubMedSearch : Chaves_2020_Molecules_25_ |
| PubMedID: 32098407 |
| Title : New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's Disease - Rajeshwari_2019_Molecules_24_587 |
| Author(s) : Rajeshwari R , Chand K , Candeias E , Cardoso SM , Chaves S , Santos MA |
| Ref : Molecules , 24 : , 2019 |
| Abstract : |
| PubMedSearch : Rajeshwari_2019_Molecules_24_587 |
| PubMedID: 30736397 |
| Title : Exploring the chelating capacity of 2-hydroxyphenyl-benzimidazole based hybrids with multi-target ability as anti-Alzheimer's agents - Chaves_2018_New.J.Chem_42_16503 |
| Author(s) : Chaves S , Hiremathad A , Tomas D , Keri RS , Piemontese L , Santos MA |
| Ref : New Journal of Chemistry , 42 :16503 , 2018 |
| Abstract : |
| PubMedSearch : Chaves_2018_New.J.Chem_42_16503 |
| PubMedID: |
| Title : Novel Tacrine-Hydroxyphenylbenzimidazole hybrids as potential multitarget drug candidates for Alzheimer's disease - Hiremathad_2018_Eur.J.Med.Chem_148_255 |
| Author(s) : Hiremathad A , Keri RS , Esteves AR , Cardoso SM , Chaves S , Santos MA |
| Ref : Eur Journal of Medicinal Chemistry , 148 :255 , 2018 |
| Abstract : |
| PubMedSearch : Hiremathad_2018_Eur.J.Med.Chem_148_255 |
| PubMedID: 29466775 |
| Title : Tacrine-deferiprone hybrids as multi-target-directed metal chelators against Alzheimer's disease: a two-in-one drug - Chand_2018_Metallomics_10_1460 |
| Author(s) : Chand K , Rajeshwari , Candeias E , Cardoso SM , Chaves S , Santos MA |
| Ref : Metallomics , 10 :1460 , 2018 |
| Abstract : |
| PubMedSearch : Chand_2018_Metallomics_10_1460 |
| PubMedID: 30183790 |
| Title : Hydroxypyridinone-benzofuran hybrids with potential protective roles for Alzheimer s disease therapy - Hiremathad_2017_J.Inorg.Biochem_179_82 |
| Author(s) : Hiremathad A , Chand K , Tolayan L , Rajeshwari , Keri RS , Esteves AR , Cardoso SM , Chaves S , Santos MA |
| Ref : J Inorg Biochem , 179 :82 , 2017 |
| Abstract : |
| PubMedSearch : Hiremathad_2017_J.Inorg.Biochem_179_82 |
| PubMedID: 29182921 |
| Title : Tacrine-(hydroxybenzoyl-pyridone) hybrids as potential multifunctional anti-Alzheimer's agents: AChE inhibition, antioxidant activity and metal chelating capacity - Chand_2016_J.Inorg.Biochem_163_266 |
| Author(s) : Chand K , Alsoghier HM , Chaves S , Santos MA |
| Ref : J Inorg Biochem , 163 :266 , 2016 |
| Abstract : |
| PubMedSearch : Chand_2016_J.Inorg.Biochem_163_266 |
| PubMedID: 27235273 |
| Title : New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease - Keri_2016_Chem.Biol.Drug.Des_87_101 |
| Author(s) : Keri RS , Quintanova C , Chaves S , Silva DF , Cardoso SM , Santos MA |
| Ref : Chemical Biology Drug Des , 87 :101 , 2016 |
| Abstract : |
| PubMedSearch : Keri_2016_Chem.Biol.Drug.Des_87_101 |
| PubMedID: 26256122 |
| Title : Copper(II) complexation of tacrine hybrids with potential anti-neurodegenerative roles - Quintanova_2015_J.Inorg.Biochem_151_58 |
| Author(s) : Quintanova C , Keri RS , Chaves S , Santos MA |
| Ref : J Inorg Biochem , 151 :58 , 2015 |
| Abstract : |
| PubMedSearch : Quintanova_2015_J.Inorg.Biochem_151_58 |
| PubMedID: 26119099 |
| Title : Insights into neurosensory toxicity of mercury in fish eyes stemming from tissue burdens, oxidative stress and synaptic transmission profiles - Pereira_2015_Mar.Environ.Res_113_70 |
| Author(s) : Pereira R , Guilherme S , Brandao F , Raimundo J , Santos MA , Pacheco M , Pereira P |
| Ref : Mar Environ Research , 113 :70 , 2015 |
| Abstract : |
| PubMedSearch : Pereira_2015_Mar.Environ.Res_113_70 |
| PubMedID: 26610197 |
| Title : Susceptibility profile of Aedes aegypti from Santiago Island, Cabo Verde, to insecticides - Rocha_2015_Acta.Trop_152_66 |
| Author(s) : Rocha HD , Paiva MH , Silva NM , de Araujo AP , Camacho DD , Moura AJ , Gomez LF , Ayres CF , Santos MA , Camacho Ddos R |
| Ref : Acta Trop , 152 :66 , 2015 |
| Abstract : |
| PubMedSearch : Rocha_2015_Acta.Trop_152_66 |
| PubMedID: 26307496 |
| Title : Multifunctional iron-chelators with protective roles against neurodegenerative diseases - Nunes_2013_Dalton.Trans_42_6058 |
| Author(s) : Nunes A , Marques SM , Quintanova C , Silva DF , Cardoso SM , Chaves S , Santos MA |
| Ref : Dalton Trans , 42 :6058 , 2013 |
| Abstract : |
| PubMedSearch : Nunes_2013_Dalton.Trans_42_6058 |
| PubMedID: 23487286 |
| Title : Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease - Keri_2013_Bioorg.Med.Chem_21_4559 |
| Author(s) : Keri RS , Quintanova C , Marques SM , Esteves AR , Cardoso SM , Santos MA |
| Ref : Bioorganic & Medicinal Chemistry , 21 :4559 , 2013 |
| Abstract : |
| PubMedSearch : Keri_2013_Bioorg.Med.Chem_21_4559 |
| PubMedID: 23768661 |
| Title : Bifunctional phenolic-choline conjugates as anti-oxidants and acetylcholinesterase inhibitors - Sebestik_2011_J.Enzyme.Inhib.Med.Chem_26_485 |
| Author(s) : Sebestik J , Marques SM , Fale PL , Santos S , Arduino DM , Cardoso SM , Oliveira CR , Serralheiro ML , Santos MA |
| Ref : J Enzyme Inhib Med Chem , 26 :485 , 2011 |
| Abstract : |
| PubMedSearch : Sebestik_2011_J.Enzyme.Inhib.Med.Chem_26_485 |
| PubMedID: 21067438 |
| Title : A single amino acid substitution in one of the lipases of Aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid - Brito-Madurro_2008_Biochem.Genet_46_557 |
| Author(s) : Brito-Madurro AG , Prade RA , Madurro JM , Santos MA , Peres NT , Cursino-Santos JR , Martinez-Rossi NM , Rossi A |
| Ref : Biochemical Genetics , 46 :557 , 2008 |
| Abstract : |
| PubMedSearch : Brito-Madurro_2008_Biochem.Genet_46_557 |
| PubMedID: 18516670 |