Full name : Martinez Gil Ana
First name : Ana
Mail : Centro de Investigaciones Biologicas (CIB-CSIC), Ramiro de Maetzu 9, Madrid
Zip Code :
City :
Country : Spain
Email : ana.martinez@csic.es
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Website :
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Comment
| Title : Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies - Jing_2023_Bioorg.Chem_134_106465 |
| Author(s) : Jing L , Wei W , Meng B , Chantegreil F , Nachon F , Martinez A , Wu G , Zhao H , Song Y , Kang D , Brazzolotto X , Zhan P , Liu X |
| Ref : Bioorg Chem , 134 :106465 , 2023 |
| Abstract : |
| PubMedSearch : Jing_2023_Bioorg.Chem_134_106465 |
| PubMedID: 36933339 |
| Gene_locus related to this paper: human-BCHE |
| Title : Functionalized aromatic esters of the Amaryllidaceae alkaloid haemanthamine and their in vitro and in silico biological activity connected to Alzheimer's disease - Perinova_2020_Bioorg.Chem_100_103928 |
| Author(s) : Perinova R , Maafi N , Korabecny J , Kohelova E , De Simone A , Al Mamun A , Hulcova D , Markova J , Kucera T , Jun D , Safratova M , Marikova J , Andrisano V , Jenco J , Kunes J , Martinez A , Novakova L , Cahlikova L |
| Ref : Bioorg Chem , 100 :103928 , 2020 |
| Abstract : |
| PubMedSearch : Perinova_2020_Bioorg.Chem_100_103928 |
| PubMedID: 32450384 |
| Title : Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease - de Andrade_2019_Bioorg.Med.Chem_27_931 |
| Author(s) : de Andrade P , Mantoani SP , Goncalves Nunes PS , Magadan CR , Perez C , Xavier DJ , Hojo ETS , Campillo NE , Martinez A , Carvalho I |
| Ref : Bioorganic & Medicinal Chemistry , 27 :931 , 2019 |
| Abstract : |
| PubMedSearch : de Andrade_2019_Bioorg.Med.Chem_27_931 |
| PubMedID: 30765302 |
| Title : Identification of new allosteric sites and modulators of AChE through computational and experimental tools - Roca_2018_J.Enzyme.Inhib.Med.Chem_33_1034 |
| Author(s) : Roca C , Requena C , Sebastian-Perez V , Malhotra S , Radoux C , Perez C , Martinez A , Antonio Paez J , Blundell TL , Campillo NE |
| Ref : J Enzyme Inhib Med Chem , 33 :1034 , 2018 |
| Abstract : |
| PubMedSearch : Roca_2018_J.Enzyme.Inhib.Med.Chem_33_1034 |
| PubMedID: 29873262 |
| Title : Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors - Chierrito_2018_Eur.J.Med.Chem_145_431 |
| Author(s) : Chierrito TPC , Pedersoli-Mantoani S , Roca C , Sebastian-Perez V , Martinez-Gonzalez L , Perez DI , Perez C , Canales A , Canada FJ , Campillo NE , Carvalho I , Martinez A |
| Ref : Eur Journal of Medicinal Chemistry , 145 :431 , 2018 |
| Abstract : |
| PubMedSearch : Chierrito_2018_Eur.J.Med.Chem_145_431 |
| PubMedID: 29335209 |
| Title : From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease - Chierrito_2017_Eur.J.Med.Chem_139_773 |
| Author(s) : Chierrito TPC , Mantoani SP , Roca C , Requena C , Sebastian-Perez V , Castillo WO , Moreira NCS , Perez C , Sakamoto-Hojo ET , Takahashi CS , Jimenez-Barbero J , Canada FJ , Campillo NE , Martinez A , Carvalho I |
| Ref : Eur Journal of Medicinal Chemistry , 139 :773 , 2017 |
| Abstract : |
| PubMedSearch : Chierrito_2017_Eur.J.Med.Chem_139_773 |
| PubMedID: 28863358 |
| Title : Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency - Rodrigues_2016_J.Clin.Lipidol_10_394 |
| Author(s) : Rodrigues R , Artieda M , Tejedor D , Martinez A , Konstantinova P , Petry H , Meyer C , Corzo D , Sundgreen C , Klor HU , Gouni-Berthold I , Westphal S , Steinhagen-Thiessen E , Julius U , Winkler K , Stroes E , Vogt A , Hardt P , Prophet H , Otte B , Nordestgaard BG , Deeb SS , Brunzell JD |
| Ref : J Clin Lipidol , 10 :394 , 2016 |
| Abstract : |
| PubMedSearch : Rodrigues_2016_J.Clin.Lipidol_10_394 |
| PubMedID: 27055971 |
| Gene_locus related to this paper: human-LPL |
| Title : Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors - Mantoani_2016_Molecules_21_ |
| Author(s) : Mantoani SP , Chierrito TP , Vilela AF , Cardoso CL , Martinez A , Carvalho I |
| Ref : Molecules , 21 : , 2016 |
| Abstract : |
| PubMedSearch : Mantoani_2016_Molecules_21_ |
| PubMedID: 26861273 |
| Title : From Bitopic Inhibitors to Multitarget Drugs for the Future Treatment of Alzheimer's Disease - Perez_2015_Curr.Med.Chem_22_3789 |
| Author(s) : Perez DI , Martinez A , Gil C , Campillo NE |
| Ref : Curr Med Chem , 22 :3789 , 2015 |
| Abstract : |
| PubMedSearch : Perez_2015_Curr.Med.Chem_22_3789 |
| PubMedID: 26264921 |
| Title : Chicago's Sanitary and Ship Canal sediment: Polycyclic aromatic hydrocarbons, polychlorinated biphenyls, brominated flame retardants, and organophosphate esters - Peverly_2015_Chemosphere_134_380 |
| Author(s) : Peverly AA , O'Sullivan C , Liu LY , Venier M , Martinez A , Hornbuckle KC , Hites RA |
| Ref : Chemosphere , 134 :380 , 2015 |
| Abstract : |
| PubMedSearch : Peverly_2015_Chemosphere_134_380 |
| PubMedID: 25981316 |
| Title : Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties - Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| Author(s) : Fernandez-Bachiller MI , Perez C , Campillo NE , Paez JA , Gonzalez-Munoz GC , Usan P , Garcia-Palomero E , Lopez MG , Villarroya M , Garcia AG , Martinez A , Rodriguez-Franco MI |
| Ref : ChemMedChem , 4 :828 , 2009 |
| Abstract : |
| PubMedSearch : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| PubMedID: 19308922 |
| Title : Potent beta-amyloid modulators - Garcia-Palomero_2008_Neurodegener.Dis_5_153 |
| Author(s) : Garcia-Palomero E , Munoz P , Usan P , Garcia P , Delgado E , de Austria C , Valenzuela R , Rubio L , Medina M , Martinez A |
| Ref : Neurodegener Dis , 5 :153 , 2008 |
| Abstract : |
| PubMedSearch : Garcia-Palomero_2008_Neurodegener.Dis_5_153 |
| PubMedID: 18322376 |
| Title : Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease - Martinez_2006_Expert.Opin.Investig.Drugs_15_1 |
| Author(s) : Martinez A , Castro A |
| Ref : Expert Opin Investig Drugs , 15 :1 , 2006 |
| Abstract : |
| PubMedSearch : Martinez_2006_Expert.Opin.Investig.Drugs_15_1 |
| PubMedID: 16370929 |
| Title : Dual binding site acetylcholinesterase inhibitors: potential new disease-modifying agents for AD - del Monte-Millan_2006_J.Mol.Neurosci_30_85 |
| Author(s) : del Monte-Millan M , Garcia-Palomero E , Valenzuela R , Usan P , de Austria C , Munoz-Ruiz P , Rubio L , Dorronsoro I , Martinez A , Medina M |
| Ref : Journal of Molecular Neuroscience , 30 :85 , 2006 |
| Abstract : |
| PubMedSearch : del Monte-Millan_2006_J.Mol.Neurosci_30_85 |
| PubMedID: 17192640 |
| Title : Targeting beta-amyloid pathogenesis through acetylcholinesterase inhibitors - Castro_2006_Curr.Pharm.Des_12_4377 |
| Author(s) : Castro A , Martinez A |
| Ref : Curr Pharm Des , 12 :4377 , 2006 |
| Abstract : |
| PubMedSearch : Castro_2006_Curr.Pharm.Des_12_4377 |
| PubMedID: 17105433 |
| Title : Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE - Alonso_2005_Bioorg.Med.Chem_13_6588 |
| Author(s) : Alonso D , Dorronsoro I , Rubio L , Munoz P , Garcia-Palomero E , del Monte M , Bidon-Chanal A , Orozco M , Luque FJ , Castro A , Medina M , Martinez A |
| Ref : Bioorganic & Medicinal Chemistry , 13 :6588 , 2005 |
| Abstract : |
| PubMedSearch : Alonso_2005_Bioorg.Med.Chem_13_6588 |
| PubMedID: 16230018 |
| Title : Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase - Rodriguez-Franco_2005_Bioorg.Med.Chem_13_6795 |
| Author(s) : Rodriguez-Franco MI , Fernandez-Bachiller MI , Perez C , Castro A , Martinez A |
| Ref : Bioorganic & Medicinal Chemistry , 13 :6795 , 2005 |
| Abstract : |
| PubMedSearch : Rodriguez-Franco_2005_Bioorg.Med.Chem_13_6795 |
| PubMedID: 16183292 |
| Title : Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease - Munoz-Ruiz_2005_J.Med.Chem_48_7223 |
| Author(s) : Munoz-Ruiz P , Rubio L , Garcia-Palomero E , Dorronsoro I , del Monte-Millan M , Valenzuela R , Usan P , de Austria C , Bartolini M , Andrisano V , Bidon-Chanal A , Orozco M , Luque FJ , Medina M , Martinez A |
| Ref : Journal of Medicinal Chemistry , 48 :7223 , 2005 |
| Abstract : |
| PubMedSearch : Munoz-Ruiz_2005_J.Med.Chem_48_7223 |
| PubMedID: 16279781 |
| Title : Synthesis and biological evaluation of tacrine-thiadiazolidinone hybrids as dual acetylcholinesterase inhibitors - Dorronsoro_2005_Arch.Pharm.(Weinheim)_338_18 |
| Author(s) : Dorronsoro I , Alonso D , Castro A , del Monte M , Garcia-Palomero E , Martinez A |
| Ref : Arch Pharm (Weinheim) , 338 :18 , 2005 |
| Abstract : |
| PubMedSearch : Dorronsoro_2005_Arch.Pharm.(Weinheim)_338_18 |
| PubMedID: 15674800 |
| Title : Peripheral and dual binding site acetylcholinesterase inhibitors: implications in treatment of Alzheimer's disease - Castro_2001_Mini.Rev.Med.Chem_1_267 |
| Author(s) : Castro A , Martinez A |
| Ref : Mini Rev Med Chem , 1 :267 , 2001 |
| Abstract : |
| PubMedSearch : Castro_2001_Mini.Rev.Med.Chem_1_267 |
| PubMedID: 12369973 |
| Title : Characterization of the lipA gene encoding the major lipase from Pseudomonas aeruginosa strain IGB83 - Martinez_2001_Appl.Microbiol.Biotechnol_56_731 |
| Author(s) : Martinez A , Soberon-Chavez G |
| Ref : Applied Microbiology & Biotechnology , 56 :731 , 2001 |
| Abstract : |
| PubMedSearch : Martinez_2001_Appl.Microbiol.Biotechnol_56_731 |
| PubMedID: 11601622 |
| Gene_locus related to this paper: pseae-llipa |
| Title : N-Benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors - Martinez_2000_Eur.J.Med.Chem_35_913 |
| Author(s) : Martinez A , Fernandez E , Castro A , Conde S , Rodriguez-Franco I , Banos JE , Badia A |
| Ref : Eur Journal of Medicinal Chemistry , 35 :913 , 2000 |
| Abstract : |
| PubMedSearch : Martinez_2000_Eur.J.Med.Chem_35_913 |
| PubMedID: 11121617 |
| Title : Lipase-catalysed synthesis of new acetylcholinesterase inhibitors: N-benzylpiperidine aminoacid derivatives - Martinez_2000_Bioorg.Med.Chem_8_731 |
| Author(s) : Martinez A , Lanot C , Perez C , Castro A , Lopez-Serrano P , Conde S |
| Ref : Bioorganic & Medicinal Chemistry , 8 :731 , 2000 |
| Abstract : |
| PubMedSearch : Martinez_2000_Bioorg.Med.Chem_8_731 |
| PubMedID: 10819162 |
| Title : Light's criteria revisited: consistency and comparison with new proposed alternative criteria for separating pleural transudates from exudates - Romero_2000_Respiration_67_18 |
| Author(s) : Romero S , Martinez A , Hernandez L , Fernandez C , Espasa A , Candela A , Martin C |
| Ref : Respiration , 67 :18 , 2000 |
| Abstract : |
| PubMedSearch : Romero_2000_Respiration_67_18 |
| PubMedID: 10705257 |
| Title : Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties - Rodriguez-Franco_2000_Arch.Pharm.(Weinheim)_333_118 |
| Author(s) : Rodriguez-Franco MI , Dorronsoro I , Martinez A , Perez C , Badia A , Banos JE |
| Ref : Arch Pharm (Weinheim) , 333 :118 , 2000 |
| Abstract : |
| PubMedSearch : Rodriguez-Franco_2000_Arch.Pharm.(Weinheim)_333_118 |
| PubMedID: 10863795 |
| Title : LipC, a second lipase of Pseudomonas aeruginosa, is LipB and Xcp dependent and is transcriptionally regulated by pilus biogenesis components - Martinez_1999_Mol.Microbiol_34_317 |
| Author(s) : Martinez A , Ostrovsky P , Nunn DN |
| Ref : Molecular Microbiology , 34 :317 , 1999 |
| Abstract : |
| PubMedSearch : Martinez_1999_Mol.Microbiol_34_317 |
| PubMedID: 10564475 |
| Gene_locus related to this paper: pseae-clipa |
| Title : Molecular modeling of (E)-1-alkyl-4(3)-[2-(1H-azolyl)vinyl]-pyridinium salts and evaluation of their behavior towards choline acetyltransferase - Alcalde_1997_Bioorg.Med.Chem_5_949 |
| Author(s) : Alcalde E , Barat A , Goya P , Martinez A , Ramirez G , Roca T , Rozas I |
| Ref : Bioorganic & Medicinal Chemistry , 5 :949 , 1997 |
| Abstract : |
| PubMedSearch : Alcalde_1997_Bioorg.Med.Chem_5_949 |
| PubMedID: 9208104 |
| Title : The sequence and expression pattern of the Calliphora erythrocephala yolk protein A and B genes - Martinez_1994_J.Mol.Evol_38_336 |
| Author(s) : Martinez A , Bownes M |
| Ref : Journal of Molecular Evolution , 38 :336 , 1994 |
| Abstract : |
| PubMedSearch : Martinez_1994_J.Mol.Evol_38_336 |
| PubMedID: 8007002 |
| Gene_locus related to this paper: caler-yolp2 , caler-yolp3 |