Cohen JB

References (37)

Title : Identifying Barbiturate Binding Sites in a Nicotinic Acetylcholine Receptor with [3H]Allyl m-Trifluoromethyldiazirine Mephobarbital, a Photoreactive Barbiturate - Hamouda_2014_Mol.Pharmacol_85_735
Author(s) : Hamouda AK , Stewart DS , Chiara DC , Savechenkov PY , Bruzik KS , Cohen JB
Ref : Molecular Pharmacology , 85 :735 , 2014
Abstract :
PubMedSearch : Hamouda_2014_Mol.Pharmacol_85_735
PubMedID: 24563544

Title : Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites! - Hamouda_2014_J.Mol.Neurosci_53_480
Author(s) : Hamouda AK , Jayakar SS , Chiara DC , Cohen JB
Ref : Journal of Molecular Neuroscience , 53 :480 , 2014
Abstract :
PubMedSearch : Hamouda_2014_J.Mol.Neurosci_53_480
PubMedID: 24158732

Title : Physostigmine and galanthamine bind in the presence of agonist at the canonical and noncanonical subunit interfaces of a nicotinic acetylcholine receptor - Hamouda_2013_J.Neurosci_33_485
Author(s) : Hamouda AK , Kimm T , Cohen JB
Ref : Journal of Neuroscience , 33 :485 , 2013
Abstract :
PubMedSearch : Hamouda_2013_J.Neurosci_33_485
PubMedID: 23303929

Title : Bupropion binds to two sites in the Torpedo nicotinic acetylcholine receptor transmembrane domain: a photoaffinity labeling study with the bupropion analogue [(125)I]-SADU-3-72 - Pandhare_2012_Biochemistry_51_2425
Author(s) : Pandhare A , Hamouda AK , Staggs B , Aggarwal S , Duddempudi PK , Lever JR , Lapinsky DJ , Jansen M , Cohen JB , Blanton MP
Ref : Biochemistry , 51 :2425 , 2012
Abstract :
PubMedSearch : Pandhare_2012_Biochemistry_51_2425
PubMedID: 22394379

Title : Multiple transmembrane binding sites for p-trifluoromethyldiazirinyl-etomidate, a photoreactive Torpedo nicotinic acetylcholine receptor allosteric inhibitor - Hamouda_2011_J.Biol.Chem_286_20466
Author(s) : Hamouda AK , Stewart DS , Husain SS , Cohen JB
Ref : Journal of Biological Chemistry , 286 :20466 , 2011
Abstract :
PubMedSearch : Hamouda_2011_J.Biol.Chem_286_20466
PubMedID: 21498509

Title : p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels - Husain_2010_J.Med.Chem_53_6432
Author(s) : Husain SS , Stewart D , Desai R , Hamouda AK , Li SG , Kelly E , Dostalova Z , Zhou X , Cotten JF , Raines DE , Olsen RW , Cohen JB , Forman SA , Miller KW
Ref : Journal of Medicinal Chemistry , 53 :6432 , 2010
Abstract :
PubMedSearch : Husain_2010_J.Med.Chem_53_6432
PubMedID: 20704351

Title : Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor - Sanghvi_2009_Biochemistry_48_9278
Author(s) : Sanghvi M , Hamouda AK , Davis MI , Morton RA , Srivastava S , Pandhare A , Duddempudi PK , Machu TK , Lovinger DM , Cohen JB , Blanton MP
Ref : Biochemistry , 48 :9278 , 2009
Abstract :
PubMedSearch : Sanghvi_2009_Biochemistry_48_9278
PubMedID: 19715355

Title : [(3)H]Epibatidine photolabels non-equivalent amino acids in the agonist binding site of Torpedo and alpha4beta2 nicotinic acetylcholine receptors - Srivastava_2009_J.Biol.Chem_284_24939
Author(s) : Srivastava S , Hamouda AK , Pandhare A , Duddempudi PK , Sanghvi M , Cohen JB , Blanton MP
Ref : Journal of Biological Chemistry , 284 :24939 , 2009
Abstract :
PubMedSearch : Srivastava_2009_J.Biol.Chem_284_24939
PubMedID: 19620239

Title : Time-resolved photolabeling of the nicotinic acetylcholine receptor by [3H]azietomidate, an open-state inhibitor - Chiara_2009_Mol.Pharmacol_75_1084
Author(s) : Chiara DC , Hong FH , Arevalo E , Husain SS , Miller KW , Forman SA , Cohen JB
Ref : Molecular Pharmacology , 75 :1084 , 2009
Abstract :
PubMedSearch : Chiara_2009_Mol.Pharmacol_75_1084
PubMedID: 19218367

Title : [(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel - Chiara_2009_Biochemistry_48_10066
Author(s) : Chiara DC , Hamouda AK , Ziebell MR , Mejia LA , Garcia G, 3rd , Cohen JB
Ref : Biochemistry , 48 :10066 , 2009
Abstract :
PubMedSearch : Chiara_2009_Biochemistry_48_10066
PubMedID: 19754159

Title : Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector - Nirthanan_2008_J.Biol.Chem_283_22051
Author(s) : Nirthanan S , Garcia G, 3rd , Chiara DC , Husain SS , Cohen JB
Ref : Journal of Biological Chemistry , 283 :22051 , 2008
Abstract :
PubMedSearch : Nirthanan_2008_J.Biol.Chem_283_22051
PubMedID: 18524766

Title : Probing the structure of the affinity-purified and lipid-reconstituted torpedo nicotinic acetylcholine receptor - Hamouda_2008_Biochemistry_47_12787
Author(s) : Hamouda AK , Chiara DC , Blanton MP , Cohen JB
Ref : Biochemistry , 47 :12787 , 2008
Abstract :
PubMedSearch : Hamouda_2008_Biochemistry_47_12787
PubMedID: 18991407

Title : Identifying the lipid-protein interface of the alpha4beta2 neuronal nicotinic acetylcholine receptor: hydrophobic photolabeling studies with 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine - Hamouda_2007_Biochemistry_46_13837
Author(s) : Hamouda AK , Sanghvi M , Chiara DC , Cohen JB , Blanton MP
Ref : Biochemistry , 46 :13837 , 2007
Abstract :
PubMedSearch : Hamouda_2007_Biochemistry_46_13837
PubMedID: 17994769

Title : [3H]Benzophenone photolabeling identifies state-dependent changes in nicotinic acetylcholine receptor structure - Garcia_2007_Biochemistry_46_10296
Author(s) : Garcia G, 3rd , Chiara DC , Nirthanan S , Hamouda AK , Stewart DS , Cohen JB
Ref : Biochemistry , 46 :10296 , 2007
Abstract :
PubMedSearch : Garcia_2007_Biochemistry_46_10296
PubMedID: 17685589

Title : Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels - Husain_2006_J.Med.Chem_49_4818
Author(s) : Husain SS , Nirthanan S , Ruesch D , Solt K , Cheng Q , Li GD , Arevalo E , Olsen RW , Raines DE , Forman SA , Cohen JB , Miller KW
Ref : Journal of Medicinal Chemistry , 49 :4818 , 2006
Abstract :
PubMedSearch : Husain_2006_J.Med.Chem_49_4818
PubMedID: 16884293

Title : alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor - Kasheverov_2006_FEBS.J_273_1373
Author(s) : Kasheverov IE , Chiara DC , Zhmak MN , Maslennikov IV , Pashkov VS , Arseniev AS , Utkin YN , Cohen JB , Tsetlin VI
Ref : Febs J , 273 :1373 , 2006
Abstract :
PubMedSearch : Kasheverov_2006_FEBS.J_273_1373
PubMedID: 16689926

Title : Cholesterol interacts with transmembrane alpha-helices M1, M3, and M4 of the Torpedo nicotinic acetylcholine receptor: photolabeling studies using [3H]Azicholesterol - Hamouda_2006_Biochemistry_45_976
Author(s) : Hamouda AK , Chiara DC , Sauls D , Cohen JB , Blanton MP
Ref : Biochemistry , 45 :976 , 2006
Abstract :
PubMedSearch : Hamouda_2006_Biochemistry_45_976
PubMedID: 16411773

Title : Neuregulin inhibits acetylcholine receptor aggregation in myotubes - Trinidad_2004_J.Biol.Chem_279_31622
Author(s) : Trinidad JC , Cohen JB
Ref : Journal of Biological Chemistry , 279 :31622 , 2004
Abstract :
PubMedSearch : Trinidad_2004_J.Biol.Chem_279_31622
PubMedID: 15155732

Title : Identification of binding sites in the nicotinic acetylcholine receptor for [3H]azietomidate, a photoactivatable general anesthetic - Ziebell_2004_J.Biol.Chem_279_17640
Author(s) : Ziebell MR , Nirthanan S , Husain SS , Miller KW , Cohen JB
Ref : Journal of Biological Chemistry , 279 :17640 , 2004
Abstract :
PubMedSearch : Ziebell_2004_J.Biol.Chem_279_17640
PubMedID: 14761946

Title : 2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels - Husain_2003_J.Med.Chem_46_1257
Author(s) : Husain SS , Ziebell MR , Ruesch D , Hong F , Arevalo E , Kosterlitz JA , Olsen RW , Forman SA , Cohen JB , Miller KW
Ref : Journal of Medicinal Chemistry , 46 :1257 , 2003
Abstract :
PubMedSearch : Husain_2003_J.Med.Chem_46_1257
PubMedID: 12646036

Title : Identification of sites of incorporation in the nicotinic acetylcholine receptor of a photoactivatible general anesthetic - Pratt_2000_J.Biol.Chem_275_29441
Author(s) : Pratt MB , Husain SS , Miller KW , Cohen JB
Ref : Journal of Biological Chemistry , 275 :29441 , 2000
Abstract :
PubMedSearch : Pratt_2000_J.Biol.Chem_275_29441
PubMedID: 10859324

Title : The Agrin\/MuSK signaling pathway is spatially segregated from the neuregulin\/ErbB receptor signaling pathway at the neuromuscular junction - Trinidad_2000_J.Neurosci_20_8762
Author(s) : Trinidad JC , Fischbach GD , Cohen JB
Ref : Journal of Neuroscience , 20 :8762 , 2000
Abstract :
PubMedSearch : Trinidad_2000_J.Neurosci_20_8762
PubMedID: 11102484

Title : Synthesis and properties of 3-(2-hydroxyethyl)-3-n-pentyldiazirine, a photoactivable general anesthetic - Husain_1999_J.Med.Chem_42_3300
Author(s) : Husain SS , Forman SA , Kloczewiak MA , Addona GH , Olsen RW , Pratt MB , Cohen JB , Miller KW
Ref : Journal of Medicinal Chemistry , 42 :3300 , 1999
Abstract :
PubMedSearch : Husain_1999_J.Med.Chem_42_3300
PubMedID: 10464016

Title : Active-site peptides of acetylcholinesterase of Electrophorus electricus: labelling of His-440 by 1-bromo-[2-14C]pinacolone and Ser- 200 by tritiated diisopropyl fluorophosphate [published erratum appears in Biochim Biophys Acta 1995 Jan 5\;1246(1):107] - Salih_1994_Biochim.Biophys.Acta_1208_324
Author(s) : Salih E , Chishti SB , Vicedomine P , Cohen SG , Chiara DC , Cohen JB
Ref : Biochimica & Biophysica Acta , 1208 :324 , 1994
Abstract :
PubMedSearch : Salih_1994_Biochim.Biophys.Acta_1208_324
PubMedID: 7947965

Title : Labeling of cysteine 231 in acetylcholinesterase from Torpedo nobiliana by the active-site directed reagent, 1-bromo-2-[14C] pinacolone. Effects of 2,2'-dipyridyl disulfide and other sulfhydryl reagents - Salih_1993_J.Biol.Chem_268_245
Author(s) : Salih E , Howard S , Chishti SB , Cohen SG , Liu WS , Cohen JB
Ref : Journal of Biological Chemistry , 268 :245 , 1993
Abstract :
PubMedSearch : Salih_1993_J.Biol.Chem_268_245
PubMedID: 8416933

Title : The 87K postsynaptic membrane protein from Torpedo is a protein-tyrosine kinase substrate homologous to dystrophin - Wagner_1993_Neuron_10_511
Author(s) : Wagner KR , Cohen JB , Huganir RL
Ref : Neuron , 10 :511 , 1993
Abstract :
PubMedSearch : Wagner_1993_Neuron_10_511
PubMedID: 8461138

Title : General occurrence of binding to acetylcholinesterase-substrate complex in noncompetitive inhibition and in inhibition by substrate - Cohen_1991_Biochim.Biophys.Acta_1076_112
Author(s) : Cohen SG , Chishti SB , Bell DA , Howard SI , Salih E , Cohen JB
Ref : Biochimica & Biophysica Acta , 1076 :112 , 1991
Abstract :
PubMedSearch : Cohen_1991_Biochim.Biophys.Acta_1076_112
PubMedID: 1986784

Title : Variation in the ratio of acetylcholine receptors and the Mr 43,000 receptor-associated protein in embryonic chick myotubes and myoblasts -
Author(s) : Tsui HC , Cohen JB , Fischbach GD
Ref : Developmental Biology , 140 :437 , 1990
PubMedID: 2373261

Title : Reactions of 1-bromo-2-[14C]pinacolone with acetylcholinesterase from Torpedo nobiliana. Effects of 5-trimethylammonio-2-pentanone and diisopropyl fluorophosphate - Cohen_1989_Biochim.Biophys.Acta_997_167
Author(s) : Cohen SG , Salih E , Solomon M , Howard S , Chishti SB , Cohen JB
Ref : Biochimica & Biophysica Acta , 997 :167 , 1989
Abstract :
PubMedSearch : Cohen_1989_Biochim.Biophys.Acta_997_167
PubMedID: 2765553

Title : A novel 87,000-Mr protein associated with acetylcholine receptors in Torpedo electric organ and vertebrate skeletal muscle - Carr_1989_J.Cell.Biol_109_1753
Author(s) : Carr C , Fischbach GD , Cohen JB
Ref : Journal of Cell Biology , 109 :1753 , 1989
Abstract :
PubMedSearch : Carr_1989_J.Cell.Biol_109_1753
PubMedID: 2793938

Title : Characterization of a snake venom neurotoxin which blocks nicotinic transmission in the avian ciliary ganglion - Loring_1984_Neurosci_11_989
Author(s) : Loring RH , Chiappinelli VA , Zigmond RE , Cohen JB
Ref : Neuroscience , 11 :989 , 1984
Abstract :
PubMedSearch : Loring_1984_Neurosci_11_989
PubMedID: 6330611

Title : Meproadifen reaction with the ionic channel of the acetylcholine receptor: potentiation of agonist-induced desensitization at the frog neuromuscular junction - Maleque_1982_Mol.Pharmacol_22_636
Author(s) : Maleque MA , Souccar C , Cohen JB , Albuquerque EX
Ref : Molecular Pharmacology , 22 :636 , 1982
Abstract :
PubMedSearch : Maleque_1982_Mol.Pharmacol_22_636
PubMedID: 6296656

Title : 1-Bromopinacolone, an active site-directed covalent inhibitor for acetylcholinesterase - Cohen_1982_J.Biol.Chem_257_14087
Author(s) : Cohen SG , Lieberman DL , Hasan FB , Cohen JB
Ref : Journal of Biological Chemistry , 257 :14087 , 1982
Abstract :
PubMedSearch : Cohen_1982_J.Biol.Chem_257_14087
PubMedID: 7142196

Title : Nicotinic postsynaptic membranes from Torpedo: sidedness, permeability to macromolecules, and topography of major polypeptides - St John_1982_J.Cell.Biol_92_333
Author(s) : St John PA , Froehner SC , Goodenough DA , Cohen JB
Ref : Journal of Cell Biology , 92 :333 , 1982
Abstract :
PubMedSearch : St John_1982_J.Cell.Biol_92_333
PubMedID: 6174528

Title : Immunofluorescence localization at the mammalian neuromuscular junction of the Mr 43,000 protein of Torpedo postsynaptic membranes - Froehner_1981_Proc.Natl.Acad.Sci.U.S.A_78_5230
Author(s) : Froehner SC , Gulbrandsen V , Hyman C , Jeng AY , Neubig RR , Cohen JB
Ref : Proc Natl Acad Sci U S A , 78 :5230 , 1981
Abstract :
PubMedSearch : Froehner_1981_Proc.Natl.Acad.Sci.U.S.A_78_5230
PubMedID: 7029531

Title : Cationic and uncharged substrates and reversible inhibitors in hydrolysis by acetylcholinesterase (EC 3.1.1.7). The trimethyl subsite - Hasan_1981_J.Biol.Chem_256_7781
Author(s) : Hasan FB , Elkind JL , Cohen SG , Cohen JB
Ref : Journal of Biological Chemistry , 256 :7781 , 1981
Abstract :
PubMedSearch : Hasan_1981_J.Biol.Chem_256_7781
PubMedID: 7263627

Title : Hydrolysis by acetylcholinesterase. Apparent molal volumes and trimethyl and methyl subsites -
Author(s) : Hasan FB , Cohen SG , Cohen JB
Ref : Journal of Biological Chemistry , 255 :3898 , 1980
PubMedID: 7372658