Dardenne LE

References (7)

Title : Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease - Macedo_2022_Bioorg.Med.Chem_71_116952
Author(s) : Macedo Vaz S , de Freitas Silva M , Dos Reis Rosa Franco G , Jorge RGM , Motta RdSF , Goncalves Castro N , Alvim Guedes I , Dardenne LE , Amaral Alves M , Garrett da Costa R , Beserra Pinheiro G , Germino Veras L , Renata Mortari M , Pruccoli L , Tarozzi A , Viegas C, Jr.
Ref : Bioorganic & Medicinal Chemistry , 71 :116952 , 2022
PubMedID: 35930852

Title : Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation - Cristancho_2022_RSC.Med.Chem_13_568
Author(s) : Cristancho Ortiz CJ , de Freitas Silva M , Pruccoli L , Fonseca Nadur N , de Azevedo LL , Kummerle AE , Guedes IA , Dardenne LE , Leomil Coelho LF , Guimaraes MJ , da Silva FMR , Castro N , Gontijo VS , Rojas VCT , de Oliveira MK , Vilela FC , Giusti-Paiva A , Barbosa G , Lima LM , Pinheiro GB , Veras LG , Mortari MR , Tarozzi A , Viegas C, Jr.
Ref : RSC Med Chem , 13 :568 , 2022
PubMedID: 35694691

Title : Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease - de Freitas Silva_2020_Molecules_25_
Author(s) : de Freitas Silva M , Tardelli Lima E , Pruccoli L , Castro NG , Guimares MJR , F MRdS , Fonseca Nadur N , de Azevedo LL , Kummerle AE , Guedes IA , Dardenne LE , Gontijo VS , Tarozzi A , Viegas C
Ref : Molecules , 25 : , 2020
PubMedID: 32664425

Title : Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling - Lopes_2019_Medchemcomm_10_2089
Author(s) : Lopes JPB , Silva L , Ceschi MA , Ludtke DS , Zimmer AR , Ruaro TC , Dantas RF , de Salles CMC , Silva-Jr FP , Senger MR , Barbosa G , Lima LM , Guedes IA , Dardenne LE
Ref : Medchemcomm , 10 :2089 , 2019
PubMedID: 32904099

Title : Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates - Dias Viegas_2018_Eur.J.Med.Chem_147_48
Author(s) : Dias Viegas FP , de Freitas Silva M , Divino da Rocha M , Castelli MR , Riquiel MM , Machado RP , Vaz SM , Simoes de Lima LM , Mancini KC , Marques de Oliveira PC , Morais EP , Gontijo VS , da Silva FMR , D'Alincourt da Fonseca Pecanha D , Castro NG , Neves GA , Giusti-Paiva A , Vilela FC , Orlandi L , Camps I , Veloso MP , Leomil Coelho LF , Ionta M , Ferreira-Silva GA , Pereira RM , Dardenne LE , Guedes IA , de Oliveira Carneiro Junior W , Quaglio Bellozi PM , Pinheiro de Oliveira AC , Ferreira FF , Pruccoli L , Tarozzi A , Viegas C, Jr.
Ref : Eur Journal of Medicinal Chemistry , 147 :48 , 2018
PubMedID: 29421570

Title : Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease - Dias_2017_Eur.J.Med.Chem_130_440
Author(s) : Dias KS , de Paula CT , Dos Santos T , Souza IN , Boni MS , Guimaraes MJ , da Silva FM , Castro NG , Neves GA , Veloso CC , Coelho MM , de Melo IS , Giusti FC , Giusti-Paiva A , da Silva ML , Dardenne LE , Guedes IA , Pruccoli L , Morroni F , Tarozzi A , Viegas C, Jr.
Ref : Eur Journal of Medicinal Chemistry , 130 :440 , 2017
PubMedID: 28282613

Title : Novel series of tacrine-tianeptine hybrids: Synthesis, cholinesterase inhibitory activity, S100B secretion and a molecular modeling approach - Ceschi_2016_Eur.J.Med.Chem_121_758
Author(s) : Ceschi MA , da Costa JS , Lopes JP , Camara VS , Campo LF , Borges AC , Goncalves CA , de Souza DF , Konrath EL , Karl AL , Guedes IA , Dardenne LE
Ref : Eur Journal of Medicinal Chemistry , 121 :758 , 2016
PubMedID: 27392529