| Title : Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease - Macedo_2022_Bioorg.Med.Chem_71_116952 |
| Author(s) : Macedo Vaz S , de Freitas Silva M , Dos Reis Rosa Franco G , Jorge RGM , Motta RdSF , Goncalves Castro N , Alvim Guedes I , Dardenne LE , Amaral Alves M , Garrett da Costa R , Beserra Pinheiro G , Germino Veras L , Renata Mortari M , Pruccoli L , Tarozzi A , Viegas C, Jr. |
| Ref : Bioorganic & Medicinal Chemistry , 71 :116952 , 2022 |
| Abstract : |
| PubMedSearch : Macedo_2022_Bioorg.Med.Chem_71_116952 |
| PubMedID: 35930852 |
| Title : Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation - Cristancho_2022_RSC.Med.Chem_13_568 |
| Author(s) : Cristancho Ortiz CJ , de Freitas Silva M , Pruccoli L , Fonseca Nadur N , de Azevedo LL , Kummerle AE , Guedes IA , Dardenne LE , Leomil Coelho LF , Guimaraes MJ , da Silva FMR , Castro N , Gontijo VS , Rojas VCT , de Oliveira MK , Vilela FC , Giusti-Paiva A , Barbosa G , Lima LM , Pinheiro GB , Veras LG , Mortari MR , Tarozzi A , Viegas C, Jr. |
| Ref : RSC Med Chem , 13 :568 , 2022 |
| Abstract : |
| PubMedSearch : Cristancho_2022_RSC.Med.Chem_13_568 |
| PubMedID: 35694691 |
| Title : Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease - de Freitas Silva_2020_Molecules_25_ |
| Author(s) : de Freitas Silva M , Tardelli Lima E , Pruccoli L , Castro NG , Guimares MJR , F MRdS , Fonseca Nadur N , de Azevedo LL , Kummerle AE , Guedes IA , Dardenne LE , Gontijo VS , Tarozzi A , Viegas C |
| Ref : Molecules , 25 : , 2020 |
| Abstract : |
| PubMedSearch : de Freitas Silva_2020_Molecules_25_ |
| PubMedID: 32664425 |
| Title : Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates - Dias Viegas_2018_Eur.J.Med.Chem_147_48 |
| Author(s) : Dias Viegas FP , de Freitas Silva M , Divino da Rocha M , Castelli MR , Riquiel MM , Machado RP , Vaz SM , Simoes de Lima LM , Mancini KC , Marques de Oliveira PC , Morais EP , Gontijo VS , da Silva FMR , D'Alincourt da Fonseca Pecanha D , Castro NG , Neves GA , Giusti-Paiva A , Vilela FC , Orlandi L , Camps I , Veloso MP , Leomil Coelho LF , Ionta M , Ferreira-Silva GA , Pereira RM , Dardenne LE , Guedes IA , de Oliveira Carneiro Junior W , Quaglio Bellozi PM , Pinheiro de Oliveira AC , Ferreira FF , Pruccoli L , Tarozzi A , Viegas C, Jr. |
| Ref : Eur Journal of Medicinal Chemistry , 147 :48 , 2018 |
| Abstract : |
| PubMedSearch : Dias Viegas_2018_Eur.J.Med.Chem_147_48 |
| PubMedID: 29421570 |
| Title : Donepezil: an important prototype to the design of new drug candidates for Alzheimer's disease - Rodrigues_2014_Mini.Rev.Med.Chem_14_2 |
| Author(s) : Rodrigues Simoes MC , Dias Viegas FP , Moreira MS , Freitas Silva M , Riquiel MM , da Rosa PM , Castelli MR , Dos Santos MH , Soares MG , Viegas C , de Freitas Silva M , Viegas C, Jr. |
| Ref : Mini Rev Med Chem , 14 :2 , 2014 |
| Abstract : |
| PubMedSearch : Rodrigues_2014_Mini.Rev.Med.Chem_14_2 |
| PubMedID: 24251806 |